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- Ulinastatin abstract "Ulinastatin (or urinary trypsin inhibitor, UTI) is a glycoprotein which acts as a trypsin inhibitor. It can be derived from urine or it can be synthetically produced. It may be effective in treatment of acute pancreatitis, chronic pancreatitis, toxic shock, Stevens–Johnson syndrome, burn patients, severe sepsis and toxic epidermal necrolysis (TEN). Currently, the drug is being used in Japan, where its brand name is Miraclid. The drug is also available in Korea, China and India. In India, it is marketed by Bharat Serums and Vaccines, Ltd. under the brand name U-Tryp, where it is indicated to treat severe sepsis and acute pancreatitis. The drug is also known by the name of Bikunin and Urinastatin.Studies in Japan have documented reduction in the incidence of ERCP-induced pancreatitis with the use of ulinastatin. In one study, the incidence of hyperenzymemia and pancreatitis was significantly lower in the ulinastatin group than in the placebo group. Ulinastatin reduced the levels of serum and drain amylase and the incidence of postoperative pancreatitis following pancreaticoduodenectomy in another study.A study conducted in India for pancreatitis concluded that, 22-day all-cause mortality in subjects with severe pancreatitis receiving ulinastatin was lower than those receiving placebo (2.8% vs 18.8%; p=0.048), resulting in a 16% absolute reduction in the risk of death and a relative reduction of 85%. Results also indicate that in this population, one life would be saved for every 6.25 subjects treated with ulinastatin. New organ dysfunction was seen in 12 subjects with severe pancreatitis on ulinastatin and 29 on placebo (p=0.0026) thus, ulinastatin reduced the rate of this complication. It also observed that the median hospital stay till discharge in survivors was shorter in the ulinastatin group, but this difference was not statistically significant.".
- Ulinastatin wikiPageID "14429866".
- Ulinastatin wikiPageLength "7553".
- Ulinastatin wikiPageOutDegree "9".
- Ulinastatin wikiPageRevisionID "676310654".
- Ulinastatin wikiPageWikiLink Acute_pancreatitis.
- Ulinastatin wikiPageWikiLink Category:Protease_inhibitors.
- Ulinastatin wikiPageWikiLink Celsius.
- Ulinastatin wikiPageWikiLink Chronic_pancreatitis.
- Ulinastatin wikiPageWikiLink Shock_(circulatory).
- Ulinastatin wikiPageWikiLink Stevens–Johnson_syndrome.
- Ulinastatin wikiPageWikiLink Toxic_epidermal_necrolysis.
- Ulinastatin wikiPageWikiLink Trypsin_inhibitor.
- Ulinastatin wikiPageWikiLink Urine.
- Ulinastatin wikiPageWikiLinkText "Ulinastatin".
- Ulinastatin wikiPageWikiLinkText "ulinastatin".
- Ulinastatin date "July 2015".
- Ulinastatin hasPhotoCollection Ulinastatin.
- Ulinastatin reason "Source refers to a Google search instead of a proper source".
- Ulinastatin wikiPageUsesTemplate Template:Better_source.
- Ulinastatin wikiPageUsesTemplate Template:Multiple_issues.
- Ulinastatin subject Category:Protease_inhibitors.
- Ulinastatin hypernym Glycoprotein.
- Ulinastatin type Drug.
- Ulinastatin type Protein.
- Ulinastatin type Drug.
- Ulinastatin type Inhibitor.
- Ulinastatin comment "Ulinastatin (or urinary trypsin inhibitor, UTI) is a glycoprotein which acts as a trypsin inhibitor. It can be derived from urine or it can be synthetically produced. It may be effective in treatment of acute pancreatitis, chronic pancreatitis, toxic shock, Stevens–Johnson syndrome, burn patients, severe sepsis and toxic epidermal necrolysis (TEN). Currently, the drug is being used in Japan, where its brand name is Miraclid. The drug is also available in Korea, China and India.".
- Ulinastatin label "Ulinastatin".
- Ulinastatin sameAs m.03d38g2.
- Ulinastatin sameAs Q7879029.
- Ulinastatin sameAs Q7879029.
- Ulinastatin wasDerivedFrom Ulinastatin?oldid=676310654.
- Ulinastatin isPrimaryTopicOf Ulinastatin.