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- Solithromycin abstract "Solithromycin (formerly known as CEM-101 and OP-1068) is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.Solithromycin exhibits excellent in vitro activity against a broad spectrum of Gram-positive respiratory tract pathogens, including macrolide-resistant strains. Solithromycin has activity against most common respiratory Gram-(+) and fastidious Gram-(-) pathogens, and is being evaluated for its utility in treating gonorrhea.May 2011: Solithromycin is in a Phase 2 clinical trial for serious community-acquired bacterial pneumonia (CABP) and in a Phase 1 clinical trial with an intravenous formulation.September 2011 : Solithromycin demonstrated comparable efficacy to levofloxacin with reduced adverse events in Phase 2 trial in people with community-acquired pneumoniaJanuary 2015: In a Phase 3 clinical trial for community-acquired bacterial pneumonia (CABP), Solithromycin administered orally demonstrated statistical non-inferiority to the fluoroquinolone, Moxifloxacin.July 2015: Patient enrollment for the second Phase 3 clinical trial (Solitaire IV) for community-acquired bacterial pneumonia (CABP) was completed with results expected in Q4 2015. ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑".
- Solithromycin atcPrefix "none".
- Solithromycin casNumber "760981-83-7".
- Solithromycin fdaUniiCode "9U1ETH79CK".
- Solithromycin iupacName "(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-{[3,4,6-trideoxy-3-(dimethylamino)-β-(D)-xylo-hexopyranosyl]oxy}-2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone".
- Solithromycin thumbnail Solithromycin.svg?width=300.
- Solithromycin wikiPageExternalLink antibacterials.
- Solithromycin wikiPageID "31036922".
- Solithromycin wikiPageLength "8565".
- Solithromycin wikiPageOutDegree "23".
- Solithromycin wikiPageRevisionID "682413048".
- Solithromycin wikiPageWikiLink Antibiotic.
- Solithromycin wikiPageWikiLink Antibiotics.
- Solithromycin wikiPageWikiLink Category:Antibiotics.
- Solithromycin wikiPageWikiLink Category:Ketolide_antibiotics.
- Solithromycin wikiPageWikiLink Category:Macrolide_antibiotics.
- Solithromycin wikiPageWikiLink Category:Macrolides.
- Solithromycin wikiPageWikiLink Category:Triazoles.
- Solithromycin wikiPageWikiLink Clinical_trial.
- Solithromycin wikiPageWikiLink Community-acquired_bacterial_pneumonia.
- Solithromycin wikiPageWikiLink Community-acquired_pneumonia.
- Solithromycin wikiPageWikiLink Gram-positive_bacteria.
- Solithromycin wikiPageWikiLink Imidazole.
- Solithromycin wikiPageWikiLink In_vitro.
- Solithromycin wikiPageWikiLink Ketolide.
- Solithromycin wikiPageWikiLink Moxifloxacin.
- Solithromycin wikiPageWikiLink Nicotinic_acetylcholine_receptor.
- Solithromycin wikiPageWikiLink Pathogen.
- Solithromycin wikiPageWikiLink Pyridine.
- Solithromycin wikiPageWikiLink Respiratory_tract_infection.
- Solithromycin wikiPageWikiLink Respiratory_tract_infections.
- Solithromycin wikiPageWikiLink Side_effect.
- Solithromycin wikiPageWikiLink Telithromycin.
- Solithromycin wikiPageWikiLink X-ray_crystallography.
- Solithromycin wikiPageWikiLinkText "Solithromycin".
- Solithromycin wikiPageWikiLinkText "solithromycin".
- Solithromycin atcPrefix "none".
- Solithromycin c "43".
- Solithromycin casNumber "760981".
- Solithromycin chembl "1240704".
- Solithromycin chemspiderid "25056854".
- Solithromycin f "1".
- Solithromycin h "65".
- Solithromycin hasPhotoCollection Solithromycin.
- Solithromycin inchi "1".
- Solithromycin inchikey "IXXFZUPTQVDPPK-ZAWHAJPIBM".
- Solithromycin iupacName "-1".
- Solithromycin legalStatus Clinical_trial.
- Solithromycin molecularWeight "845.01".
- Solithromycin n "6".
- Solithromycin o "10".
- Solithromycin routesOfAdministration "oral, intravenous".
- Solithromycin smiles "CC[C@@H]1[C@@]2C".
- Solithromycin stdinchi "1".
- Solithromycin stdinchikey "IXXFZUPTQVDPPK-ZAWHAJPISA-N".
- Solithromycin synonyms "CEM-101; OP-1068".
- Solithromycin unii "9".
- Solithromycin verifiedfields "changed".
- Solithromycin verifiedrevid "417774847".
- Solithromycin width "250".
- Solithromycin wikiPageUsesTemplate Template:Antibiotic-stub.
- Solithromycin wikiPageUsesTemplate Template:Drugbox.
- Solithromycin wikiPageUsesTemplate Template:Macrolides,_lincosamides_and_streptogramins.
- Solithromycin wikiPageUsesTemplate Template:Reflist.
- Solithromycin subject Category:Antibiotics.
- Solithromycin subject Category:Ketolide_antibiotics.
- Solithromycin subject Category:Macrolide_antibiotics.
- Solithromycin subject Category:Macrolides.
- Solithromycin subject Category:Triazoles.
- Solithromycin hypernym Development.
- Solithromycin type Article.
- Solithromycin type ChemicalSubstance.
- Solithromycin type Drug.
- Solithromycin type Article.
- Solithromycin type Azole.
- Solithromycin type Chemical.
- Solithromycin type Drug.
- Solithromycin type Lactone.
- Solithromycin type Macrocycle.
- Solithromycin type Product.
- Solithromycin type ChemicalObject.
- Solithromycin type Thing.
- Solithromycin type Q8386.
- Solithromycin comment "Solithromycin (formerly known as CEM-101 and OP-1068) is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.Solithromycin exhibits excellent in vitro activity against a broad spectrum of Gram-positive respiratory tract pathogens, including macrolide-resistant strains.".
- Solithromycin label "Solithromycin".
- Solithromycin sameAs m.0gg905w.
- Solithromycin sameAs Q7558263.
- Solithromycin sameAs Q7558263.
- Solithromycin wasDerivedFrom Solithromycin?oldid=682413048.
- Solithromycin depiction Solithromycin.svg.
- Solithromycin isPrimaryTopicOf Solithromycin.