Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/SH-053-R-CH3-2′F> ?p ?o }
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- SH-053-R-CH3-2′F abstract "SH-053-R-CH3-2′F is a drug used in scientific research which is a benzodiazepine derivative. It produces some of the same effects as other benzodiazepines, but is much more subtype-selective than most other drugs of this class, having high selectivity, binding affinity and efficacy at the α5 subtype of the GABAA receptor. This gives much tighter control of the effects produced, and so while SH-053-R-CH3-2′F retains sedative and anxiolytic effects, it does not cause ataxia at moderate doses. SH-053-R-CH3-2′F also blocks the nootropic effects of the α5-selective inverse agonist PWZ-029, so amnesia is also a likely side effect.".
- SH-053-R-CH3-2′F casNumber "872874-14-1".
- SH-053-R-CH3-2′F iupacName "(R)-8-ethynyl-6-(2-fluorophenyl)-4-methyl-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid ethyl ester".
- SH-053-R-CH3-2′F pubchem "11574585".
- SH-053-R-CH3-2′F thumbnail SH053RCH32F_structure.png?width=300.
- SH-053-R-CH3-2′F wikiPageID "22232677".
- SH-053-R-CH3-2′F wikiPageLength "2488".
- SH-053-R-CH3-2′F wikiPageOutDegree "22".
- SH-053-R-CH3-2′F wikiPageRevisionID "669041436".
- SH-053-R-CH3-2′F wikiPageWikiLink Amnesia.
- SH-053-R-CH3-2′F wikiPageWikiLink Anxiolytic.
- SH-053-R-CH3-2′F wikiPageWikiLink Ataxia.
- SH-053-R-CH3-2′F wikiPageWikiLink Benzodiazepine.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Alkynes.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Benzodiazepines.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Carboxylate_esters.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Ethyl_esters.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:GABAA_receptor_positive_allosteric_modulators.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Hypnotics.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Imidazobenzodiazepines.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Organofluorides.
- SH-053-R-CH3-2′F wikiPageWikiLink Category:Sedatives.
- SH-053-R-CH3-2′F wikiPageWikiLink Dissociation_constant.
- SH-053-R-CH3-2′F wikiPageWikiLink Efficacy.
- SH-053-R-CH3-2′F wikiPageWikiLink GABAA_receptor.
- SH-053-R-CH3-2′F wikiPageWikiLink GABRA5.
- SH-053-R-CH3-2′F wikiPageWikiLink Inverse_agonist.
- SH-053-R-CH3-2′F wikiPageWikiLink Nootropic.
- SH-053-R-CH3-2′F wikiPageWikiLink PWZ-029.
- SH-053-R-CH3-2′F wikiPageWikiLink QH-II-66.
- SH-053-R-CH3-2′F wikiPageWikiLink QH-ii-066.
- SH-053-R-CH3-2′F wikiPageWikiLink Sedative.
- SH-053-R-CH3-2′F wikiPageWikiLinkText "SH-053-R-CH3-2′F".
- SH-053-R-CH3-2′F c "23".
- SH-053-R-CH3-2′F casNumber "872874".
- SH-053-R-CH3-2′F f "1".
- SH-053-R-CH3-2′F h "18".
- SH-053-R-CH3-2′F hasPhotoCollection SH-053-R-CH3-2′F.
- SH-053-R-CH3-2′F iupacName "-8".
- SH-053-R-CH3-2′F molecularWeight "387.406".
- SH-053-R-CH3-2′F n "3".
- SH-053-R-CH3-2′F o "2".
- SH-053-R-CH3-2′F pubchem "11574585".
- SH-053-R-CH3-2′F smiles "Fc2ccccc2C1=NCc3cncn3-cc1cc4C#C".
- SH-053-R-CH3-2′F width "220".
- SH-053-R-CH3-2′F wikiPageUsesTemplate Template:Benzodiazepines.
- SH-053-R-CH3-2′F wikiPageUsesTemplate Template:Drugbox.
- SH-053-R-CH3-2′F wikiPageUsesTemplate Template:GABAAR_PAMs.
- SH-053-R-CH3-2′F wikiPageUsesTemplate Template:Pharma-stub.
- SH-053-R-CH3-2′F wikiPageUsesTemplate Template:Reflist.
- SH-053-R-CH3-2′F subject Category:Alkynes.
- SH-053-R-CH3-2′F subject Category:Benzodiazepines.
- SH-053-R-CH3-2′F subject Category:Carboxylate_esters.
- SH-053-R-CH3-2′F subject Category:Ethyl_esters.
- SH-053-R-CH3-2′F subject Category:GABAA_receptor_positive_allosteric_modulators.
- SH-053-R-CH3-2′F subject Category:Hypnotics.
- SH-053-R-CH3-2′F subject Category:Imidazobenzodiazepines.
- SH-053-R-CH3-2′F subject Category:Organofluorides.
- SH-053-R-CH3-2′F subject Category:Sedatives.
- SH-053-R-CH3-2′F type ChemicalSubstance.
- SH-053-R-CH3-2′F type Drug.
- SH-053-R-CH3-2′F type ChemicalObject.
- SH-053-R-CH3-2′F type Thing.
- SH-053-R-CH3-2′F type Q8386.
- SH-053-R-CH3-2′F comment "SH-053-R-CH3-2′F is a drug used in scientific research which is a benzodiazepine derivative. It produces some of the same effects as other benzodiazepines, but is much more subtype-selective than most other drugs of this class, having high selectivity, binding affinity and efficacy at the α5 subtype of the GABAA receptor. This gives much tighter control of the effects produced, and so while SH-053-R-CH3-2′F retains sedative and anxiolytic effects, it does not cause ataxia at moderate doses.".
- SH-053-R-CH3-2′F label "SH-053-R-CH3-2′F".
- SH-053-R-CH3-2′F sameAs m.05q4nrd.
- SH-053-R-CH3-2′F sameAs SH-053-R-CH3-2′F.
- SH-053-R-CH3-2′F sameAs SH-053-R-CH3-2′F.
- SH-053-R-CH3-2′F sameAs Q7390120.
- SH-053-R-CH3-2′F sameAs Q7390120.
- SH-053-R-CH3-2′F wasDerivedFrom SH-053-R-CH3-2′F?oldid=669041436.
- SH-053-R-CH3-2′F depiction SH053RCH32F_structure.png.
- SH-053-R-CH3-2′F isPrimaryTopicOf SH-053-R-CH3-2′F.