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- SB-699551 abstract "SB-699551 is a drug which was the first compound developed to act as a selective antagonist for the serotonin receptor 5-HT5A, with selectivity of around 100x over other serotonin receptor subtypes. The function of the 5-HT5A receptor remains poorly defined, but SB-699551 was found to modulate serotonin release from neurons, suggesting it acts as a presynaptic inhibitory autoreceptor similar to the 5-HT1B and 5-HT1D receptors. Multiple therapeutic roles have been suggested for 5-HT5A ligands due to the presence of this receptor in several areas of the brain, but research is still at an early stage.".
- SB-699551 casNumber "791789-61-2".
- SB-699551 iupacName "3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-([(2-phenylethyl)amino]methyl)-4-biphenylyl)methyl]propanamide".
- SB-699551 thumbnail SB-699,551_structure.png?width=300.
- SB-699551 wikiPageID "20290534".
- SB-699551 wikiPageLength "2918".
- SB-699551 wikiPageOutDegree "8".
- SB-699551 wikiPageRevisionID "642357067".
- SB-699551 wikiPageWikiLink 5-HT1B_receptor.
- SB-699551 wikiPageWikiLink 5-HT1D_receptor.
- SB-699551 wikiPageWikiLink 5-HT5A_receptor.
- SB-699551 wikiPageWikiLink Antagonist_(pharmacology).
- SB-699551 wikiPageWikiLink Category:5-HT5_antagonists.
- SB-699551 wikiPageWikiLink Category:Amides.
- SB-699551 wikiPageWikiLink Category:Amines.
- SB-699551 wikiPageWikiLink Receptor_antagonist.
- SB-699551 wikiPageWikiLink Serotonin.
- SB-699551 wikiPageWikiLinkText "SB-699551".
- SB-699551 c "34".
- SB-699551 casNumber "791789".
- SB-699551 h "45".
- SB-699551 hasPhotoCollection SB-699551.
- SB-699551 iupacName "3".
- SB-699551 molecularWeight "511.739".
- SB-699551 n "3".
- SB-699551 o "1".
- SB-699551 smiles "C2CCCC2CCCNCcccc3-cccc1CNCCc4ccccc4".
- SB-699551 verifiedrevid "449560048".
- SB-699551 width "240".
- SB-699551 wikiPageUsesTemplate Template:Drugbox.
- SB-699551 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- SB-699551 wikiPageUsesTemplate Template:Reflist.
- SB-699551 wikiPageUsesTemplate Template:Serotonergics.
- SB-699551 subject Category:5-HT5_antagonists.
- SB-699551 subject Category:Amides.
- SB-699551 subject Category:Amines.
- SB-699551 hypernym Drug.
- SB-699551 type ChemicalSubstance.
- SB-699551 type Drug.
- SB-699551 type ChemicalObject.
- SB-699551 type Thing.
- SB-699551 type Q8386.
- SB-699551 comment "SB-699551 is a drug which was the first compound developed to act as a selective antagonist for the serotonin receptor 5-HT5A, with selectivity of around 100x over other serotonin receptor subtypes. The function of the 5-HT5A receptor remains poorly defined, but SB-699551 was found to modulate serotonin release from neurons, suggesting it acts as a presynaptic inhibitory autoreceptor similar to the 5-HT1B and 5-HT1D receptors.".
- SB-699551 label "SB-699551".
- SB-699551 sameAs m.04zxrb8.
- SB-699551 sameAs SB-699,551.
- SB-699551 sameAs SB-699,551.
- SB-699551 sameAs Q80311.
- SB-699551 sameAs Q80311.
- SB-699551 wasDerivedFrom SB-699551?oldid=642357067.
- SB-699551 depiction SB-699,551_structure.png.
- SB-699551 isPrimaryTopicOf SB-699551.