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- SB-258585 abstract "SB-258585 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT6 receptor antagonist, with a Ki of 8.9nM. It is used in its 125I radiolabelled form to map the distribution of 5-HT6 receptors in the brain.SB-258585 and other 5-HT6 antagonists show nootropic effects in animal studies, as well as antidepressant and anxiolytic effects, and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease.".
- SB-258585 casNumber "209480-63-7".
- SB-258585 iupacName "4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide".
- SB-258585 pubchem "3248571".
- SB-258585 thumbnail SB258585.png?width=300.
- SB-258585 wikiPageID "19828883".
- SB-258585 wikiPageLength "5707".
- SB-258585 wikiPageOutDegree "16".
- SB-258585 wikiPageRevisionID "667227494".
- SB-258585 wikiPageWikiLink 5-HT6_receptor.
- SB-258585 wikiPageWikiLink Alzheimers_disease.
- SB-258585 wikiPageWikiLink Antagonist_(pharmacology).
- SB-258585 wikiPageWikiLink Antidepressant.
- SB-258585 wikiPageWikiLink Anxiolytic.
- SB-258585 wikiPageWikiLink Category:5-HT6_antagonists.
- SB-258585 wikiPageWikiLink Category:Iodoarenes.
- SB-258585 wikiPageWikiLink Category:Phenol_ethers.
- SB-258585 wikiPageWikiLink Category:Piperazines.
- SB-258585 wikiPageWikiLink Category:Sulfonamides.
- SB-258585 wikiPageWikiLink Dissociation_constant.
- SB-258585 wikiPageWikiLink Iodine-125.
- SB-258585 wikiPageWikiLink Isotopic_labeling.
- SB-258585 wikiPageWikiLink Nootropic.
- SB-258585 wikiPageWikiLink Receptor_(biochemistry).
- SB-258585 wikiPageWikiLink Receptor_antagonist.
- SB-258585 wikiPageWikiLink Schizophrenia.
- SB-258585 wikiPageWikiLinkText "SB-258585".
- SB-258585 c "18".
- SB-258585 casNumber "209480".
- SB-258585 chembl "60264".
- SB-258585 chemspiderid "2498938".
- SB-258585 h "22".
- SB-258585 hasPhotoCollection SB-258585.
- SB-258585 i "1".
- SB-258585 inchi "1".
- SB-258585 inchikey "BDHMSYNBSBZCAF-UHFFFAOYAR".
- SB-258585 iupacName "4".
- SB-258585 iupharLigand "3232".
- SB-258585 molecularWeight "487.354".
- SB-258585 n "3".
- SB-258585 o "3".
- SB-258585 pubchem "3248571".
- SB-258585 s "1".
- SB-258585 smiles "C3CNCCN3c1ccNSc2ccccc2".
- SB-258585 stdinchi "1".
- SB-258585 stdinchikey "BDHMSYNBSBZCAF-UHFFFAOYSA-N".
- SB-258585 verifiedfields "changed".
- SB-258585 verifiedrevid "449586800".
- SB-258585 width "240".
- SB-258585 wikiPageUsesTemplate Template:Drugbox.
- SB-258585 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- SB-258585 wikiPageUsesTemplate Template:Piperazines.
- SB-258585 wikiPageUsesTemplate Template:Reflist.
- SB-258585 wikiPageUsesTemplate Template:Serotonergics.
- SB-258585 subject Category:5-HT6_antagonists.
- SB-258585 subject Category:Iodoarenes.
- SB-258585 subject Category:Phenol_ethers.
- SB-258585 subject Category:Piperazines.
- SB-258585 subject Category:Sulfonamides.
- SB-258585 hypernym Drug.
- SB-258585 type ChemicalSubstance.
- SB-258585 type Drug.
- SB-258585 type ChemicalObject.
- SB-258585 type Thing.
- SB-258585 type Q8386.
- SB-258585 comment "SB-258585 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT6 receptor antagonist, with a Ki of 8.9nM.".
- SB-258585 label "SB-258585".
- SB-258585 sameAs SB-258,585.
- SB-258585 sameAs m.04q1xxt.
- SB-258585 sameAs SB-258,585.
- SB-258585 sameAs SB-258,585.
- SB-258585 sameAs Q855518.
- SB-258585 sameAs Q855518.
- SB-258585 wasDerivedFrom SB-258585?oldid=667227494.
- SB-258585 depiction SB258585.png.
- SB-258585 isPrimaryTopicOf SB-258585.