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- RRM1 abstract "Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene.This gene encodes one of two non-identical subunits which constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. This gene is oriented in a head-to-tail configuration with the stromal interaction molecule 1 gene (STIM1), with the 3' end of STIM1 situated 1.6 kb from the 5' end of this gene.".
- RRM1 entrezgene "6240".
- RRM1 wikiPageID "15884649".
- RRM1 wikiPageLength "8061".
- RRM1 wikiPageOutDegree "4".
- RRM1 wikiPageRevisionID "679031289".
- RRM1 wikiPageWikiLink Category:EC_1.17.4.
- RRM1 wikiPageWikiLink Enzyme.
- RRM1 wikiPageWikiLink Gene.
- RRM1 wikiPageWikiLink Ribonucleotide_reductase.
- RRM1 wikiPageWikiLinkText "RRM1".
- RRM1 wikiPageWikiLinkText "ribonucleotide reductase M1 polypeptide".
- RRM1 hasPhotoCollection RRM1.
- RRM1 requireManualInspection "no".
- RRM1 summaryText "300.0".
- RRM1 updateCitations "yes".
- RRM1 updatePage "yes".
- RRM1 updateProteinBox "yes".
- RRM1 updateSummary "yes".
- RRM1 wikiPageUsesTemplate Template:FluoropyrimidineActivity_WP1601.
- RRM1 wikiPageUsesTemplate Template:Gene-11-stub.
- RRM1 wikiPageUsesTemplate Template:PBB.
- RRM1 wikiPageUsesTemplate Template:PBB_Controls.
- RRM1 wikiPageUsesTemplate Template:PBB_Further_reading.
- RRM1 wikiPageUsesTemplate Template:PBB_Summary.
- RRM1 wikiPageUsesTemplate Template:Refbegin.
- RRM1 wikiPageUsesTemplate Template:Refend.
- RRM1 wikiPageUsesTemplate Template:Reflist.
- RRM1 subject Category:EC_1.17.4.
- RRM1 hypernym Enzyme.
- RRM1 type Biomolecule.
- RRM1 type Protein.
- RRM1 type Thing.
- RRM1 type Q206229.
- RRM1 type Q8054.
- RRM1 comment "Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene.This gene encodes one of two non-identical subunits which constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region.".
- RRM1 label "RRM1".
- RRM1 sameAs m.03qdjnc.
- RRM1 sameAs Q7277644.
- RRM1 sameAs Q7277644.
- RRM1 wasDerivedFrom RRM1?oldid=679031289.
- RRM1 isPrimaryTopicOf RRM1.