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- Pump_leak_model abstract "In nephrology, the pump leak model is a mechanism for the reabsorption of sodium in the kidney nephrons, in order to achieve and maintain the fluid-balanced euvolemic state within the human body.The "pump" is the active transport of sodium from the tubular cell into the interstitial space at the basolateral membrane, via carrier proteins, i.e. Na+/K+ ATPase. The "leak" results from the action of active transport (of the Na+/K+ ATPase), which creates a diffusion gradient that opposes its own action by favouring back-diffusion.Sodium is passively transported from the tubular fluid into the tubular cells at the apical membrane (via ion channels), and then actively pumped out of the tubular cells at the basolateral membrane (via Na+/K+ ATPase), which then enters the blood.The pump-leak model explains the relationship between the transport of ions and cellular metabolism.".
- Pump_leak_model wikiPageID "9020298".
- Pump_leak_model wikiPageLength "1067".
- Pump_leak_model wikiPageOutDegree "9".
- Pump_leak_model wikiPageRevisionID "641414358".
- Pump_leak_model wikiPageWikiLink ATPase.
- Pump_leak_model wikiPageWikiLink Active_transport.
- Pump_leak_model wikiPageWikiLink Category:Nephrology.
- Pump_leak_model wikiPageWikiLink Diffusion_MRI.
- Pump_leak_model wikiPageWikiLink Diffusion_gradient.
- Pump_leak_model wikiPageWikiLink Euvolemia.
- Pump_leak_model wikiPageWikiLink Fluid_balance.
- Pump_leak_model wikiPageWikiLink Kidney.
- Pump_leak_model wikiPageWikiLink Nephrology.
- Pump_leak_model wikiPageWikiLink Nephron.
- Pump_leak_model wikiPageWikiLink Sodium.
- Pump_leak_model hasPhotoCollection Pump_leak_model.
- Pump_leak_model wikiPageUsesTemplate Template:Cell-biology-stub.
- Pump_leak_model wikiPageUsesTemplate Template:Multiple_issues.
- Pump_leak_model subject Category:Nephrology.
- Pump_leak_model hypernym Mechanism.
- Pump_leak_model type Article.
- Pump_leak_model type Organisation.
- Pump_leak_model type Article.
- Pump_leak_model type Specialty.
- Pump_leak_model comment "In nephrology, the pump leak model is a mechanism for the reabsorption of sodium in the kidney nephrons, in order to achieve and maintain the fluid-balanced euvolemic state within the human body.The "pump" is the active transport of sodium from the tubular cell into the interstitial space at the basolateral membrane, via carrier proteins, i.e. Na+/K+ ATPase.".
- Pump_leak_model label "Pump leak model".
- Pump_leak_model sameAs m.027tr31.
- Pump_leak_model sameAs Q7259813.
- Pump_leak_model sameAs Q7259813.
- Pump_leak_model wasDerivedFrom Pump_leak_model?oldid=641414358.
- Pump_leak_model isPrimaryTopicOf Pump_leak_model.