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- Penicilloic_acid abstract "Penicilloic acid is any of several acids which are obtained from the penicillins by the hydrolytic opening of the lactam ring (as by the action of a beta-lactamase).Hypersensitivity is the most important adverse effect of the penicillins. The major antigenic determinant of penicillin hypersensitivity is its metabolite, penicilloic acid, which reacts with proteins and serves as a hapten to cause an immune reaction. Approximately five percent of patients have some kind of reaction, ranging from maculopapular rash (the most common rash seen with ampicillin hypersensitivity) to angioedema (marked swelling of the lips, tongue, and periorbital area) and anaphylaxis. Among patients with mononucleosis who are treated with ampicillin, the incidence of maculopapular rash approaches 100 percent. Cross-allergic reactions occur among the β-lactam antibiotics. To determine whether treatment with a β-lactam is safe when an allergy is noted, patient history regarding severity of previous reaction is essential.".
- Penicilloic_acid iupacName "(2R,4S)-2-[(R)-Carboxy(formamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid".
- Penicilloic_acid thumbnail Penicilloic_acid.png?width=300.
- Penicilloic_acid wikiPageID "42982295".
- Penicilloic_acid wikiPageLength "2126".
- Penicilloic_acid wikiPageOutDegree "20".
- Penicilloic_acid wikiPageRevisionID "677896947".
- Penicilloic_acid wikiPageWikiLink Allergic_reactions.
- Penicilloic_acid wikiPageWikiLink Allergy.
- Penicilloic_acid wikiPageWikiLink Ampicillin.
- Penicilloic_acid wikiPageWikiLink Anaphylaxis.
- Penicilloic_acid wikiPageWikiLink Angioedema.
- Penicilloic_acid wikiPageWikiLink Antigen.
- Penicilloic_acid wikiPageWikiLink Antigenic.
- Penicilloic_acid wikiPageWikiLink Beta-lactamase.
- Penicilloic_acid wikiPageWikiLink Category:Carboxylic_acids.
- Penicilloic_acid wikiPageWikiLink Category:Human_drug_metabolites.
- Penicilloic_acid wikiPageWikiLink Category:Thiazolidines.
- Penicilloic_acid wikiPageWikiLink Hapten.
- Penicilloic_acid wikiPageWikiLink Hydrolysis.
- Penicilloic_acid wikiPageWikiLink Hydrolytic.
- Penicilloic_acid wikiPageWikiLink Hypersensitivity.
- Penicilloic_acid wikiPageWikiLink Immune_reaction.
- Penicilloic_acid wikiPageWikiLink Immune_system.
- Penicilloic_acid wikiPageWikiLink Infectious_mononucleosis.
- Penicilloic_acid wikiPageWikiLink Lactam.
- Penicilloic_acid wikiPageWikiLink Maculopapular_rash.
- Penicilloic_acid wikiPageWikiLink Metabolite.
- Penicilloic_acid wikiPageWikiLink Mononucleosis.
- Penicilloic_acid wikiPageWikiLink Penicillin.
- Penicilloic_acid wikiPageWikiLink Penicillins.
- Penicilloic_acid wikiPageWikiLink Periorbita.
- Penicilloic_acid wikiPageWikiLink Periorbital.
- Penicilloic_acid wikiPageWikiLink Β-lactam_antibiotic.
- Penicilloic_acid date "June 2014".
- Penicilloic_acid hasPhotoCollection Penicilloic_acid.
- Penicilloic_acid imagealt "Structure of penicilloic acid".
- Penicilloic_acid imagefile "File:Penicilloic acid.png".
- Penicilloic_acid iupacname "-2".
- Penicilloic_acid othernames "Penicilloic acid".
- Penicilloic_acid wikiPageUsesTemplate Template:Chembox.
- Penicilloic_acid wikiPageUsesTemplate Template:Molecular-cell-biology-stub.
- Penicilloic_acid wikiPageUsesTemplate Template:Orphan.
- Penicilloic_acid wikiPageUsesTemplate Template:Reflist.
- Penicilloic_acid subject Category:Carboxylic_acids.
- Penicilloic_acid subject Category:Human_drug_metabolites.
- Penicilloic_acid subject Category:Thiazolidines.
- Penicilloic_acid type ChemicalCompound.
- Penicilloic_acid type ChemicalSubstance.
- Penicilloic_acid type ChemicalObject.
- Penicilloic_acid type Thing.
- Penicilloic_acid type Q11173.
- Penicilloic_acid comment "Penicilloic acid is any of several acids which are obtained from the penicillins by the hydrolytic opening of the lactam ring (as by the action of a beta-lactamase).Hypersensitivity is the most important adverse effect of the penicillins. The major antigenic determinant of penicillin hypersensitivity is its metabolite, penicilloic acid, which reacts with proteins and serves as a hapten to cause an immune reaction.".
- Penicilloic_acid label "Penicilloic acid".
- Penicilloic_acid sameAs m.010s5cnd.
- Penicilloic_acid sameAs Q18387473.
- Penicilloic_acid sameAs Q18387473.
- Penicilloic_acid wasDerivedFrom Penicilloic_acid?oldid=677896947.
- Penicilloic_acid depiction Penicilloic_acid.png.
- Penicilloic_acid isPrimaryTopicOf Penicilloic_acid.