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- PSORT abstract "PSORT is a bioinformatics tool used for the prediction of protein localisation sites in cells. It receives the information of an amino acid sequence and its taxon of origin (e.g. Gram-negative bacteria) as inputs. Then it analyses the input sequence by applying the stored rules for various sequence features of known protein sorting signals. Finally, it reports the possibility for the input protein to be localised at each candidate site with additional information.Researchers using this tool can predict with some degree of reason, where in a cell a protein is most likely to localise to. This is because proteins are localised by cell machinery that recognises signal peptide sequences (similar to a postal address) and moves the protein the appropriate location. The signal peptide is often cleaved off after the destination is reached. PSORT uses known signal peptide sequences to analyse and predict what an input sequence is most likely to cause a localisation to.Protein localisation is important because it supports a proposed role that a protein may have. For instance, catalase enzymes (proteins that convert peroxide into water and oxygen) should be expected to localise to a peroxisome because that is an area of high peroxide activity. By analysing a signal peptide sequence and visual localisation by GFP expression, strong evidence is obtained for this role.The program was written by Dr Kenta Nakai from the Human Genome Center at the Institute for Medical Science, University of Tokyo, Japan and is available free for all users.".
- PSORT thumbnail Cell_structure.png?width=300.
- PSORT wikiPageExternalLink psort.nibb.ac.jp.
- PSORT wikiPageID "4901423".
- PSORT wikiPageLength "2586".
- PSORT wikiPageOutDegree "14".
- PSORT wikiPageRevisionID "679005330".
- PSORT wikiPageWikiLink Amino_acid.
- PSORT wikiPageWikiLink Bioinformatics.
- PSORT wikiPageWikiLink Category:Bioinformatics_software.
- PSORT wikiPageWikiLink Category:Protein_targeting.
- PSORT wikiPageWikiLink Cell_(biology).
- PSORT wikiPageWikiLink Gram-negative_bacteria.
- PSORT wikiPageWikiLink Green_fluorescent_protein.
- PSORT wikiPageWikiLink Human_Genome_Center_at_the_Institute_for_Medical_Science.
- PSORT wikiPageWikiLink Information.
- PSORT wikiPageWikiLink Kenta_Nakai.
- PSORT wikiPageWikiLink Signal_peptide.
- PSORT wikiPageWikiLink Subcellular_localisation.
- PSORT wikiPageWikiLink Subcellular_localization.
- PSORT wikiPageWikiLink University_of_Tokyo.
- PSORT wikiPageWikiLink File:Cell_structure.png.
- PSORT wikiPageWikiLinkText "Kenta Nakai".
- PSORT wikiPageWikiLinkText "PSORT".
- PSORT hasPhotoCollection PSORT.
- PSORT wikiPageUsesTemplate Template:Reflist.
- PSORT subject Category:Bioinformatics_software.
- PSORT subject Category:Protein_targeting.
- PSORT hypernym Tool.
- PSORT type Software.
- PSORT comment "PSORT is a bioinformatics tool used for the prediction of protein localisation sites in cells. It receives the information of an amino acid sequence and its taxon of origin (e.g. Gram-negative bacteria) as inputs. Then it analyses the input sequence by applying the stored rules for various sequence features of known protein sorting signals.".
- PSORT label "PSORT".
- PSORT sameAs PSORT.
- PSORT sameAs m.0ct8ps.
- PSORT sameAs Q2044701.
- PSORT sameAs Q2044701.
- PSORT wasDerivedFrom PSORT?oldid=679005330.
- PSORT depiction Cell_structure.png.
- PSORT isPrimaryTopicOf PSORT.
