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- PKM2 abstract "Pyruvate kinase isozymes M1/M2 also known as pyruvate kinase muscle isozyme (PKM), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting protein 3 (OIP3) is an enzyme that in humans is encoded by the PKM2 gene.PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. Depending upon the different metabolic functions of the tissues, different isoenzymes of pyruvate kinase are expressed. The pyruvate kinase isoenzyme type M2 is expressed in some differentiated tissues, such as lung, fat tissue, retina, and pancreatic islets, as well as in all cells with a high rate of nucleic acid synthesis, such as normal proliferating cells, embryonic cells, and especially tumor cells.Two isozymes are encoded by the PKM gene: M1-PK and M2-PK. The M-gene consists of 12 exons and 11 introns. PKM1 and PKM2 are different splicing products of the M-gene (exon 9 for PKM1 and exon 10 for PKM2) and solely differ in 23 amino acids within a 56-amino acid stretch (aa 378-434) at their carboxy terminus. The M1-PK isozyme is expressed in organs that are strongly dependent upon a high rate of energy regeneration, such as muscle and brain.".
- PKM2 entrezgene "5315".
- PKM2 wikiPageExternalLink m2-pk.html.
- PKM2 wikiPageID "15817440".
- PKM2 wikiPageLength "25981".
- PKM2 wikiPageOutDegree "33".
- PKM2 wikiPageRevisionID "681384102".
- PKM2 wikiPageWikiLink Adenosine_triphosphate.
- PKM2 wikiPageWikiLink Amino_acid.
- PKM2 wikiPageWikiLink Amino_acids.
- PKM2 wikiPageWikiLink Bloom_syndrome.
- PKM2 wikiPageWikiLink Brain.
- PKM2 wikiPageWikiLink Category:Enzymes.
- PKM2 wikiPageWikiLink Category:Metabolism.
- PKM2 wikiPageWikiLink Enolase.
- PKM2 wikiPageWikiLink Enzyme.
- PKM2 wikiPageWikiLink Gene.
- PKM2 wikiPageWikiLink Glyceraldehyde_3-phosphate_dehydrogenase.
- PKM2 wikiPageWikiLink Glycolysis.
- PKM2 wikiPageWikiLink Glycolytic_enzyme_complex.
- PKM2 wikiPageWikiLink Hexokinase.
- PKM2 wikiPageWikiLink Isoenzyme.
- PKM2 wikiPageWikiLink Isozyme.
- PKM2 wikiPageWikiLink Lactate_dehydrogenase.
- PKM2 wikiPageWikiLink Muscle.
- PKM2 wikiPageWikiLink Nucleic_acid.
- PKM2 wikiPageWikiLink Nucleic_acids.
- PKM2 wikiPageWikiLink Phosphoenolpyruvate.
- PKM2 wikiPageWikiLink Phosphoenolpyruvic_acid.
- PKM2 wikiPageWikiLink Phosphoglycerate_kinase.
- PKM2 wikiPageWikiLink Phosphoglycerate_mutase.
- PKM2 wikiPageWikiLink Phosphoglyceromutase.
- PKM2 wikiPageWikiLink Phospholipid.
- PKM2 wikiPageWikiLink Phospholipids.
- PKM2 wikiPageWikiLink Pyruvate.
- PKM2 wikiPageWikiLink Pyruvate_kinase.
- PKM2 wikiPageWikiLink Pyruvic_acid.
- PKM2 wikiPageWikiLink Tumor_M2-PK.
- PKM2 wikiPageWikiLink Warburg_effect.
- PKM2 wikiPageWikiLinkText "PKM2".
- PKM2 hasPhotoCollection PKM2.
- PKM2 wikiPageUsesTemplate Template:Cite_web.
- PKM2 wikiPageUsesTemplate Template:GlycolysisGluconeogenesis_WP534.
- PKM2 wikiPageUsesTemplate Template:Glycolysis_enzymes.
- PKM2 wikiPageUsesTemplate Template:MeshName.
- PKM2 wikiPageUsesTemplate Template:PBB.
- PKM2 wikiPageUsesTemplate Template:PDB_Gallery.
- PKM2 wikiPageUsesTemplate Template:Reflist.
- PKM2 subject Category:Enzymes.
- PKM2 subject Category:Metabolism.
- PKM2 hypernym Enzyme.
- PKM2 type Biomolecule.
- PKM2 type Protein.
- PKM2 type Process.
- PKM2 type Thing.
- PKM2 type Q206229.
- PKM2 type Q8054.
- PKM2 comment "Pyruvate kinase isozymes M1/M2 also known as pyruvate kinase muscle isozyme (PKM), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting protein 3 (OIP3) is an enzyme that in humans is encoded by the PKM2 gene.PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. Depending upon the different metabolic functions of the tissues, different isoenzymes of pyruvate kinase are expressed.".
- PKM2 label "PKM2".
- PKM2 sameAs Penapis_tumor_M2-PK.
- PKM2 sameAs m.03nwr1w.
- PKM2 sameAs Q7119512.
- PKM2 sameAs Q7119512.
- PKM2 wasDerivedFrom PKM2?oldid=681384102.
- PKM2 isPrimaryTopicOf PKM2.