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- Nucleosome_Repeat_Length abstract "Nucleosome Repeat Length (NRL) is the average distance between the centers of neighboring nucleosomes. NRL is an important physical chromatin property that determines its biological function. NRL can be determined genome-wide for the chromatin in a given cell type and state, or locally for a large enough genomic region containing several nucleosomes.In chromatin neighboring nucleosomes are separated by the linker DNA and in many cases also by the linker histone H1 as well as non-histone proteins. Since the size of the nucleosome is typically fixed (146-147 base pairs), NRL is mostly determined by the size of the linker region between nucleosomes. Alternatively, partial DNA unwrapping from the histone octamer or partial disassembly of the histone octamer can decrease the effective nucleosome size and thus affect NRL.Past studies going back to 1970s showed that, in general, NRL is different for different species and even for different cell types of the same organism. In addition, recent publications reported NRL variations for different genomic regions of the same cell type. Recent works have compared the NRL around yeast transcription start sites (TSSs) in vivo and that for the reconstituted chromatin on the same DNA sequences in vitro. It was shown that ordered nucleosome positioning arises only in the presence of ATP-dependent chromatin remodeling. Furthermore, it was reported that the NRL determined around yeast TSSs is an invariant value universal for a given wild type yeast strain, although it can change when one of chromatin remodelers is missing. In general, NRL depends on the DNA sequence, concentrations of histones and non-histone proteins, as well as long-range interactions between nucleosomes. NRL determines geometric properties of the nucleosome array, and therefore the higher-order packing of the DNA into the chromatin fiber, which might affect gene expression.".
- Nucleosome_Repeat_Length wikiPageID "46978792".
- Nucleosome_Repeat_Length wikiPageLength "4873".
- Nucleosome_Repeat_Length wikiPageOutDegree "23".
- Nucleosome_Repeat_Length wikiPageRevisionID "669558044".
- Nucleosome_Repeat_Length wikiPageWikiLink Adenosine_triphosphate.
- Nucleosome_Repeat_Length wikiPageWikiLink Category:DNA.
- Nucleosome_Repeat_Length wikiPageWikiLink Category:Epigenetics.
- Nucleosome_Repeat_Length wikiPageWikiLink Category:Molecular_biology.
- Nucleosome_Repeat_Length wikiPageWikiLink Category:Molecular_genetics.
- Nucleosome_Repeat_Length wikiPageWikiLink Category:Nuclear_substructures.
- Nucleosome_Repeat_Length wikiPageWikiLink Chromatin.
- Nucleosome_Repeat_Length wikiPageWikiLink Chromatin_fiber.
- Nucleosome_Repeat_Length wikiPageWikiLink Chromatin_remodelers.
- Nucleosome_Repeat_Length wikiPageWikiLink Chromatin_remodeling.
- Nucleosome_Repeat_Length wikiPageWikiLink DNA.
- Nucleosome_Repeat_Length wikiPageWikiLink Gene_expression.
- Nucleosome_Repeat_Length wikiPageWikiLink Histone.
- Nucleosome_Repeat_Length wikiPageWikiLink Histone_H1.
- Nucleosome_Repeat_Length wikiPageWikiLink Histone_octamer.
- Nucleosome_Repeat_Length wikiPageWikiLink Histones.
- Nucleosome_Repeat_Length wikiPageWikiLink Linker_DNA.
- Nucleosome_Repeat_Length wikiPageWikiLink Nucleosome.
- Nucleosome_Repeat_Length wikiPageWikiLink Nucleosomes.
- Nucleosome_Repeat_Length wikiPageWikiLink Protein.
- Nucleosome_Repeat_Length wikiPageWikiLink Proteins.
- Nucleosome_Repeat_Length wikiPageWikiLinkText "Nucleosome Repeat Length".
- Nucleosome_Repeat_Length hasPhotoCollection Nucleosome_Repeat_Length.
- Nucleosome_Repeat_Length wikiPageUsesTemplate Template:Chromo.
- Nucleosome_Repeat_Length wikiPageUsesTemplate Template:Gene_expression.
- Nucleosome_Repeat_Length wikiPageUsesTemplate Template:Molecular_Biology.
- Nucleosome_Repeat_Length wikiPageUsesTemplate Template:Nucleus.
- Nucleosome_Repeat_Length wikiPageUsesTemplate Template:Reflist.
- Nucleosome_Repeat_Length subject Category:DNA.
- Nucleosome_Repeat_Length subject Category:Epigenetics.
- Nucleosome_Repeat_Length subject Category:Molecular_biology.
- Nucleosome_Repeat_Length subject Category:Molecular_genetics.
- Nucleosome_Repeat_Length subject Category:Nuclear_substructures.
- Nucleosome_Repeat_Length hypernym Distance.
- Nucleosome_Repeat_Length type Agent.
- Nucleosome_Repeat_Length comment "Nucleosome Repeat Length (NRL) is the average distance between the centers of neighboring nucleosomes. NRL is an important physical chromatin property that determines its biological function.".
- Nucleosome_Repeat_Length label "Nucleosome Repeat Length".
- Nucleosome_Repeat_Length sameAs m.013f3q2_.
- Nucleosome_Repeat_Length wasDerivedFrom Nucleosome_Repeat_Length?oldid=669558044.
- Nucleosome_Repeat_Length isPrimaryTopicOf Nucleosome_Repeat_Length.