Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Nomifensine> ?p ?o }
- Nomifensine abstract "Nomifensine (Merital, Alival) is a norepinephrine-dopamine reuptake inhibitor, i.e. a drug that increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. This is a mechanism of action shared by some recreational drugs like cocaine and the medication Tametraline (see DRI). Research showed that the (S) isomer is responsible for activity.The drug was developed in the 1960s by Hoechst AG (now Sanofi-Aventis), who then test marketed it in the United States. It was an effective antidepressant, without sedative effects. Nomifensine did not interact significantly with alcohol and lacked anticholinergic effects. No withdrawal symptoms were seen after 6 months treatment. The drug was however considered not suitable for agitated patients as it presumably made agitation worse.In January 1986 the drug was withdrawn by its manufacturers for safety reasons.Some case reports in the 1980s suggested that there was potential for psychological dependence on nomifensine, typically in patients with a history of stimulant addiction, or when the drug was used in very high doses (400–600 mg per day).In a 1989 study it has been investigated for use in treating adult ADHD and proven successful. In a 1977 study it has not proven of benefit in advanced parkinsonism, except for depression associated with the parkinsonism.".
- Nomifensine atcPrefix "N06".
- Nomifensine atcSuffix "AX04".
- Nomifensine casNumber "24526-64-5".
- Nomifensine chEBI "116225".
- Nomifensine drugbank "DB04821".
- Nomifensine fdaUniiCode "1LGS5JRP31".
- Nomifensine iupacName "(±)-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine".
- Nomifensine pubchem "4528".
- Nomifensine thumbnail Nomifensine2DCSD.svg?width=300.
- Nomifensine wikiPageID "3281168".
- Nomifensine wikiPageLength "9203".
- Nomifensine wikiPageOutDegree "28".
- Nomifensine wikiPageRevisionID "679020723".
- Nomifensine wikiPageWikiLink ADHD.
- Nomifensine wikiPageWikiLink Amineptine.
- Nomifensine wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- Nomifensine wikiPageWikiLink Category:Anilines.
- Nomifensine wikiPageWikiLink Category:Antidepressants.
- Nomifensine wikiPageWikiLink Category:Norepinephrine-dopamine_reuptake_inhibitors.
- Nomifensine wikiPageWikiLink Category:Stimulants.
- Nomifensine wikiPageWikiLink Category:Tetrahydroisoquinolines.
- Nomifensine wikiPageWikiLink Category:Withdrawn_drugs.
- Nomifensine wikiPageWikiLink Cocaine.
- Nomifensine wikiPageWikiLink Dopamine_reuptake_inhibitor.
- Nomifensine wikiPageWikiLink Drowsiness.
- Nomifensine wikiPageWikiLink Dry_mouth.
- Nomifensine wikiPageWikiLink Food_and_Drug_Administration.
- Nomifensine wikiPageWikiLink Haemolytic_anaemia.
- Nomifensine wikiPageWikiLink Headache.
- Nomifensine wikiPageWikiLink Hemolytic_anemia.
- Nomifensine wikiPageWikiLink Hoechst_AG.
- Nomifensine wikiPageWikiLink Insomnia.
- Nomifensine wikiPageWikiLink Norepinephrine-dopamine_reuptake_inhibitor.
- Nomifensine wikiPageWikiLink Palpitations.
- Nomifensine wikiPageWikiLink Perafensine.
- Nomifensine wikiPageWikiLink Renal_failure.
- Nomifensine wikiPageWikiLink Sanofi.
- Nomifensine wikiPageWikiLink Sanofi-Aventis.
- Nomifensine wikiPageWikiLink Somnolence.
- Nomifensine wikiPageWikiLink Structure–activity_relationship.
- Nomifensine wikiPageWikiLink Tachycardia.
- Nomifensine wikiPageWikiLink Tametraline.
- Nomifensine wikiPageWikiLink Test_market.
- Nomifensine wikiPageWikiLink United_States.
- Nomifensine wikiPageWikiLink Xerostomia.
- Nomifensine wikiPageWikiLink File:Nomifensine_synthesis.png.
- Nomifensine wikiPageWikiLinkText "Nomifensine".
- Nomifensine wikiPageWikiLinkText "nomifensine".
- Nomifensine atcPrefix "N06".
- Nomifensine atcSuffix "AX04".
- Nomifensine c "16".
- Nomifensine casNumber "24526".
- Nomifensine chebi "116225".
- Nomifensine chembl "273575".
- Nomifensine chemspiderid "4371".
- Nomifensine drugbank "DB04821".
- Nomifensine eliminationHalfLife "-14400.0".
- Nomifensine excretion "86400.0".
- Nomifensine h "18".
- Nomifensine hasPhotoCollection Nomifensine.
- Nomifensine image "Nomifensine3DanJ.gif".
- Nomifensine inchi "1".
- Nomifensine inchikey "XXPANQJNYNUNES-UHFFFAOYAL".
- Nomifensine iupacName "-2".
- Nomifensine iupharLigand "4792".
- Nomifensine legalStatus "Rx-only".
- Nomifensine molecularWeight "238.328".
- Nomifensine n "2".
- Nomifensine pubchem "4528".
- Nomifensine routesOfAdministration "Oral".
- Nomifensine smiles "NC1=CC=CC2=C1CNCC2C3=CC=CC=C3".
- Nomifensine stdinchi "1".
- Nomifensine stdinchikey "XXPANQJNYNUNES-UHFFFAOYSA-N".
- Nomifensine unii "1".
- Nomifensine verifiedfields "changed".
- Nomifensine verifiedrevid "462262394".
- Nomifensine watchedfields "changed".
- Nomifensine width "200".
- Nomifensine width "250".
- Nomifensine wikiPageUsesTemplate Template:Adrenergics.
- Nomifensine wikiPageUsesTemplate Template:Antidepressants.
- Nomifensine wikiPageUsesTemplate Template:Drugbox.
- Nomifensine wikiPageUsesTemplate Template:Reflist.
- Nomifensine wikiPageUsesTemplate Template:Stimulants.
- Nomifensine subject Category:Anilines.
- Nomifensine subject Category:Antidepressants.
- Nomifensine subject Category:Norepinephrine-dopamine_reuptake_inhibitors.
- Nomifensine subject Category:Stimulants.
- Nomifensine subject Category:Tetrahydroisoquinolines.
- Nomifensine subject Category:Withdrawn_drugs.
- Nomifensine hypernym Inhibitor.
- Nomifensine type Article.
- Nomifensine type ChemicalSubstance.
- Nomifensine type Drug.
- Nomifensine type Article.
- Nomifensine type Chemical.
- Nomifensine type Drug.
- Nomifensine type Enamine.
- Nomifensine type Heterocycle.
