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- Nitric_oxide_dioxygenase abstract "Nitric oxide dioxygenase (EC 1.14.12.17) is an enzyme that catalyzes the conversion of nitric oxide (NO) to nitrate (NO−3). The net reaction for the reaction catalyzed by nitric oxide dioxygenase is shown below: 2NO + 2O2 + NAD(P)H → 2NO3− + NAD(P)+ + H+Nitric oxide is a ubiquitous small molecule that is integrated in a wide variety of physiological processes including smooth muscle vasodilation, platelet disaggregation, neurotransmission, and immune response to bacterial infection. Overproduction of this signaling molecule can be lethal to cells by poisoning cellular energy production. The most sensitive targets of NO are aconitase, an enzyme that catalyzes the isomerization of citrate to isocitrate in the citric acid cycle, and cytochrome oxidase, the last enzyme in the respiratory electron transport chain of mitochondria. Additionally NO, with its lone radical on the nitrogen atom, is implicated in a number of secondary mechanisms of toxicity, including catalase inhibition (resulting in hydrogen peroxide toxicity), Fe-S center iron liberation, and the formation of dinitosyl-iron complexes.Due to the potential lethality of NO, cells benefitted greatly from the evolution of an enzyme capable of catalyzing the conversion of toxic NO to nitrate. A 'nitric oxide dioxygenase' is an enzyme that is capable of carrying out this reaction. NO dioxygenase belongs to the family of oxidoreductases, more specifically those acting on paired donors, with O2 as oxidant and with incorporation of two atoms of oxygen into the other donor.".
- Nitric_oxide_dioxygenase ecNumber "1.14.12.17".
- Nitric_oxide_dioxygenase thumbnail PDB_1gvh.jpg?width=300.
- Nitric_oxide_dioxygenase wikiPageID "14045844".
- Nitric_oxide_dioxygenase wikiPageLength "20764".
- Nitric_oxide_dioxygenase wikiPageOutDegree "32".
- Nitric_oxide_dioxygenase wikiPageRevisionID "646724333".
- Nitric_oxide_dioxygenase wikiPageWikiLink Aconitase.
- Nitric_oxide_dioxygenase wikiPageWikiLink Catalase.
- Nitric_oxide_dioxygenase wikiPageWikiLink Category:EC_1.14.12.
- Nitric_oxide_dioxygenase wikiPageWikiLink Category:Enzymes_of_unknown_structure.
- Nitric_oxide_dioxygenase wikiPageWikiLink Category:NADH-dependent_enzymes.
- Nitric_oxide_dioxygenase wikiPageWikiLink Category:NADPH-dependent_enzymes.
- Nitric_oxide_dioxygenase wikiPageWikiLink Citrate.
- Nitric_oxide_dioxygenase wikiPageWikiLink Cytochrome_c_oxidase.
- Nitric_oxide_dioxygenase wikiPageWikiLink Cytochrome_oxidase.
- Nitric_oxide_dioxygenase wikiPageWikiLink Cytoglobin.
- Nitric_oxide_dioxygenase wikiPageWikiLink Enzyme.
- Nitric_oxide_dioxygenase wikiPageWikiLink Escherichia_coli.
- Nitric_oxide_dioxygenase wikiPageWikiLink Felix_Hoppe-Seyler.
- Nitric_oxide_dioxygenase wikiPageWikiLink Globin.
- Nitric_oxide_dioxygenase wikiPageWikiLink Hemoglobin.
- Nitric_oxide_dioxygenase wikiPageWikiLink Imidazole.
- Nitric_oxide_dioxygenase wikiPageWikiLink Isocitrate.
- Nitric_oxide_dioxygenase wikiPageWikiLink Isocitric_acid.
- Nitric_oxide_dioxygenase wikiPageWikiLink Leghemoglobin.
- Nitric_oxide_dioxygenase wikiPageWikiLink Myoglobin.
- Nitric_oxide_dioxygenase wikiPageWikiLink Neuroglobin.
- Nitric_oxide_dioxygenase wikiPageWikiLink Nicotinamide_adenine_dinucleotide_phosphate.
- Nitric_oxide_dioxygenase wikiPageWikiLink Nitrate.
- Nitric_oxide_dioxygenase wikiPageWikiLink Nitric_oxide.
- Nitric_oxide_dioxygenase wikiPageWikiLink Oxidoreductase.
- Nitric_oxide_dioxygenase wikiPageWikiLink Oxidoreductase_FAD-binding_domain.
- Nitric_oxide_dioxygenase wikiPageWikiLink Oxidoreductase_NAD-binding_domain.
- Nitric_oxide_dioxygenase wikiPageWikiLink Peroxidase.
- Nitric_oxide_dioxygenase wikiPageWikiLink Rhodobacter_sphaeroides.
- Nitric_oxide_dioxygenase wikiPageWikiLink Superoxide_dismutase.
- Nitric_oxide_dioxygenase wikiPageWikiLinkText "Nitric oxide dioxygenase".
- Nitric_oxide_dioxygenase wikiPageWikiLinkText "nitric oxide dioxygenase".
- Nitric_oxide_dioxygenase b "3".
- Nitric_oxide_dioxygenase caption "E. coli flavohemoglobin/NOD structure. green = reductase domain, blue = hemoglobin domain.".
- Nitric_oxide_dioxygenase casNumber "214466".
- Nitric_oxide_dioxygenase ecNumber "1.14".
- Nitric_oxide_dioxygenase goCode "8941".
- Nitric_oxide_dioxygenase hasPhotoCollection Nitric_oxide_dioxygenase.
- Nitric_oxide_dioxygenase iubmbEcNumber "1".
- Nitric_oxide_dioxygenase name "nitric oxide dioxygenase".
- Nitric_oxide_dioxygenase p "−".
- Nitric_oxide_dioxygenase wikiPageUsesTemplate Template:EC_number.
- Nitric_oxide_dioxygenase wikiPageUsesTemplate Template:Enzyme.
- Nitric_oxide_dioxygenase wikiPageUsesTemplate Template:Refbegin.
- Nitric_oxide_dioxygenase wikiPageUsesTemplate Template:Refend.
- Nitric_oxide_dioxygenase wikiPageUsesTemplate Template:Reflist.
- Nitric_oxide_dioxygenase wikiPageUsesTemplate Template:Su.
- Nitric_oxide_dioxygenase subject Category:EC_1.14.12.
- Nitric_oxide_dioxygenase subject Category:Enzymes_of_unknown_structure.
- Nitric_oxide_dioxygenase subject Category:NADH-dependent_enzymes.
- Nitric_oxide_dioxygenase subject Category:NADPH-dependent_enzymes.
- Nitric_oxide_dioxygenase hypernym Enzyme.
- Nitric_oxide_dioxygenase type Biomolecule.
- Nitric_oxide_dioxygenase type Enzyme.
- Nitric_oxide_dioxygenase type Protein.
- Nitric_oxide_dioxygenase type Thing.
- Nitric_oxide_dioxygenase type Q206229.
- Nitric_oxide_dioxygenase type Q8047.
- Nitric_oxide_dioxygenase comment "Nitric oxide dioxygenase (EC 1.14.12.17) is an enzyme that catalyzes the conversion of nitric oxide (NO) to nitrate (NO−3). The net reaction for the reaction catalyzed by nitric oxide dioxygenase is shown below: 2NO + 2O2 + NAD(P)H → 2NO3− + NAD(P)+ + H+Nitric oxide is a ubiquitous small molecule that is integrated in a wide variety of physiological processes including smooth muscle vasodilation, platelet disaggregation, neurotransmission, and immune response to bacterial infection.".
- Nitric_oxide_dioxygenase label "Nitric oxide dioxygenase".
- Nitric_oxide_dioxygenase sameAs حمض_النتريك_دي-أكسجيناز.
- Nitric_oxide_dioxygenase sameAs Ossido_nitrico_diossigenasi.
- Nitric_oxide_dioxygenase sameAs 一酸化窒素ジオキシゲナーゼ.
- Nitric_oxide_dioxygenase sameAs m.03cr_7r.
- Nitric_oxide_dioxygenase sameAs Azot-monoksid_dioksigenaza.
- Nitric_oxide_dioxygenase sameAs Azot-monoksid_dioksigenaza.
- Nitric_oxide_dioxygenase sameAs Q3878102.
- Nitric_oxide_dioxygenase sameAs Q3878102.
- Nitric_oxide_dioxygenase wasDerivedFrom Nitric_oxide_dioxygenase?oldid=646724333.
- Nitric_oxide_dioxygenase depiction PDB_1gvh.jpg.
- Nitric_oxide_dioxygenase isPrimaryTopicOf Nitric_oxide_dioxygenase.
- Nitric_oxide_dioxygenase name "nitric oxide dioxygenase".