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- NE-100 abstract "NE-100 or 4-methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine is a selective sigma-1 receptor antagonist, with a reported binding affinity of Ki = 1.03 ± 0.01 nM, and more than 205 times selectivity over the sigma-2 receptor.NE-100 was one of the earliest selective sigma-1 receptor ligands reported and has been widely used as a pharmacological tool. The original, eight step synthesis of NE-100 was reported by Atsuro Nakazato and colleagues of Taisho Pharmaceutical Company in 1999. More recently, Michael Kassiou and co-workers have reported a more expedient synthesis of NE-100 that proceeds in 56% unoptimized yield over 4 steps.".
- NE-100 casNumber "149860-29-7".
- NE-100 iupacName "4-methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine".
- NE-100 pubchem "9841596".
- NE-100 thumbnail NE-100.png?width=300.
- NE-100 wikiPageID "36145115".
- NE-100 wikiPageLength "3959".
- NE-100 wikiPageOutDegree "5".
- NE-100 wikiPageRevisionID "667235121".
- NE-100 wikiPageWikiLink Antagonist.
- NE-100 wikiPageWikiLink Binding_affinity.
- NE-100 wikiPageWikiLink Category:Phenol_ethers.
- NE-100 wikiPageWikiLink Ligand_(biochemistry).
- NE-100 wikiPageWikiLink Sigma-1_receptor.
- NE-100 wikiPageWikiLink Sigma-2_receptor.
- NE-100 wikiPageWikiLinkText "NE-100".
- NE-100 c "23".
- NE-100 casNumber "149860".
- NE-100 chemspiderid "8017311".
- NE-100 h "33".
- NE-100 hasPhotoCollection NE-100.
- NE-100 inchi "1".
- NE-100 inchikey "YBLIQJGXRLZBCZ-UHFFFAOYAC".
- NE-100 iupacName "4".
- NE-100 iupharLigand "6679".
- NE-100 molecularWeight "355.51".
- NE-100 n "1".
- NE-100 o "2".
- NE-100 pubchem "9841596".
- NE-100 smiles "CCCNCCC1=CCOCCC2=CC=CC=C2".
- NE-100 stdinchi "1".
- NE-100 stdinchikey "YBLIQJGXRLZBCZ-UHFFFAOYSA-N".
- NE-100 wikiPageUsesTemplate Template:Drugbox.
- NE-100 wikiPageUsesTemplate Template:Reflist.
- NE-100 wikiPageUsesTemplate Template:Sigmaergics.
- NE-100 subject Category:Phenol_ethers.
- NE-100 hypernym Antagonist.
- NE-100 type Article.
- NE-100 type ChemicalSubstance.
- NE-100 type Drug.
- NE-100 type Article.
- NE-100 type Chemical.
- NE-100 type Ether.
- NE-100 type ChemicalObject.
- NE-100 type Thing.
- NE-100 type Q8386.
- NE-100 comment "NE-100 or 4-methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine is a selective sigma-1 receptor antagonist, with a reported binding affinity of Ki = 1.03 ± 0.01 nM, and more than 205 times selectivity over the sigma-2 receptor.NE-100 was one of the earliest selective sigma-1 receptor ligands reported and has been widely used as a pharmacological tool. The original, eight step synthesis of NE-100 was reported by Atsuro Nakazato and colleagues of Taisho Pharmaceutical Company in 1999.".
- NE-100 label "NE-100".
- NE-100 sameAs m.0k0tmm3.
- NE-100 sameAs Q6953369.
- NE-100 sameAs Q6953369.
- NE-100 wasDerivedFrom NE-100?oldid=667235121.
- NE-100 depiction NE-100.png.
- NE-100 isPrimaryTopicOf NE-100.