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N-Methylcarfentanil abstract "N-Methylcarfentanil (R-32395) is an opioid analgesic drug related to the highly potent animal tranquilizer carfentanil, but several thousand times weaker, being only slightly stronger than morphine. It was first synthesised by a team of chemists at Janssen Pharmaceutica led by Paul Janssen, who were investigating the structure-activity relationships of the fentanyl family of drugs. They found that replacing the phenethyl group attached to the piperidine nitrogen of fentanyl with a smaller methyl group, made it so much weaker that it was inactive as an analgesic in animals. However the same change made to the more potent analogue carfentanil retained reasonable opioid receptor activity, reflecting the higher binding affinity produced by the 4-carbomethoxy group.".
N-Methylcarfentanil iupacName "Methyl 1-methyl-4-(N-phenylpropionamido)piperidine-4-carboxylate".
N-Methylcarfentanil thumbnail N-methylcarfentanil_structure.png?width=300.
N-Methylcarfentanil wikiPageID "32356813".
N-Methylcarfentanil wikiPageLength "3148".
N-Methylcarfentanil wikiPageOutDegree "15".
N-Methylcarfentanil wikiPageRevisionID "678462325".
N-Methylcarfentanil wikiPageWikiLink Carfentanil.
N-Methylcarfentanil wikiPageWikiLink Category:Anilides.
N-Methylcarfentanil wikiPageWikiLink Category:Carboxylate_esters.
N-Methylcarfentanil wikiPageWikiLink Category:Mu-opioid_agonists.
N-Methylcarfentanil wikiPageWikiLink Category:Piperidines.
N-Methylcarfentanil wikiPageWikiLink Category:Propionamides.
N-Methylcarfentanil wikiPageWikiLink Category:Synthetic_opioids.
N-Methylcarfentanil wikiPageWikiLink Dissociation_constant.
N-Methylcarfentanil wikiPageWikiLink Fentanyl.
N-Methylcarfentanil wikiPageWikiLink Janssen_Pharmaceutica.
N-Methylcarfentanil wikiPageWikiLink Morphine.
N-Methylcarfentanil wikiPageWikiLink Opioid.
N-Methylcarfentanil wikiPageWikiLink Opioid_receptor.
N-Methylcarfentanil wikiPageWikiLink Paul_Janssen.
N-Methylcarfentanil wikiPageWikiLink Structure-activity_relationship.
N-Methylcarfentanil wikiPageWikiLink Structure–activity_relationship.
N-Methylcarfentanil wikiPageWikiLinkText "N-Methylcarfentanil".
N-Methylcarfentanil wikiPageWikiLinkText "N-Methylcarfentanyl".
N-Methylcarfentanil bioavailability "?".
N-Methylcarfentanil c "17".
N-Methylcarfentanil chemspiderid "26231037".
N-Methylcarfentanil drugName "N-Methylcarfentanil".
N-Methylcarfentanil excretion "?".
N-Methylcarfentanil h "24".
N-Methylcarfentanil hasPhotoCollection N-Methylcarfentanil.
N-Methylcarfentanil iupacName "Methyl 1-methyl-4-piperidine-4-carboxylate".
N-Methylcarfentanil metabolism "?".
N-Methylcarfentanil molecularWeight "304.384".
N-Methylcarfentanil n "2".
N-Methylcarfentanil o "3".
N-Methylcarfentanil pregnancyCategory "?".
N-Methylcarfentanil proteinBound "?".
N-Methylcarfentanil smiles "O=CC1CCNCC1".
N-Methylcarfentanil stdinchi "1".
N-Methylcarfentanil stdinchikey "KKEVIELPQLXPRR-UHFFFAOYSA-N".
N-Methylcarfentanil verifiedrevid "445639339".
N-Methylcarfentanil width "200".
N-Methylcarfentanil wikiPageUsesTemplate Template:Drugbox.
N-Methylcarfentanil wikiPageUsesTemplate Template:Opioidergics.
N-Methylcarfentanil subject Category:Anilides.
N-Methylcarfentanil subject Category:Carboxylate_esters.
N-Methylcarfentanil subject Category:Mu-opioid_agonists.
N-Methylcarfentanil subject Category:Piperidines.
N-Methylcarfentanil subject Category:Propionamides.
N-Methylcarfentanil subject Category:Synthetic_opioids.
N-Methylcarfentanil hypernym Drug.
N-Methylcarfentanil type Article.
N-Methylcarfentanil type ChemicalSubstance.
N-Methylcarfentanil type Drug.
N-Methylcarfentanil type Agonist.
N-Methylcarfentanil type Amide.
N-Methylcarfentanil type Article.
N-Methylcarfentanil type Chemical.
N-Methylcarfentanil type Ester.
N-Methylcarfentanil type Heterocycle.
N-Methylcarfentanil type Opioid.
N-Methylcarfentanil type ChemicalObject.
N-Methylcarfentanil type Thing.
N-Methylcarfentanil type Q8386.
N-Methylcarfentanil comment "N-Methylcarfentanil (R-32395) is an opioid analgesic drug related to the highly potent animal tranquilizer carfentanil, but several thousand times weaker, being only slightly stronger than morphine. It was first synthesised by a team of chemists at Janssen Pharmaceutica led by Paul Janssen, who were investigating the structure-activity relationships of the fentanyl family of drugs.".
N-Methylcarfentanil label "N-Methylcarfentanil".
N-Methylcarfentanil sameAs m.0gyvlsx.
N-Methylcarfentanil sameAs N-Metilkarfentanil.
N-Methylcarfentanil sameAs N-Metilkarfentanil.
N-Methylcarfentanil sameAs Q6951377.
N-Methylcarfentanil sameAs Q6951377.
N-Methylcarfentanil wasDerivedFrom N-Methylcarfentanil?oldid=678462325.
N-Methylcarfentanil depiction N-methylcarfentanil_structure.png.
N-Methylcarfentanil isPrimaryTopicOf N-Methylcarfentanil.
N-Methylcarfentanil name "N-Methylcarfentanil".