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- Laudanosine abstract "Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium. Laudanosine also occurs naturally in minute amounts (0.1%) in opium, from which it was first isolated in 1871. Partial dehydrogenation of laudanosine will lead to papaverine, the alkaloid found in the opium poppy plant (Papaver somniferum).Laudanosine is a benzyltetrahydroisoquinoline alkaloid. It has been shown to interact with GABA receptors, glycine receptors, opioid receptors, and nicotinic acetylcholine receptors, but not benzodiazepine or muscarinic receptors which are also involved in epilepsy and other types of seizures.".
- Laudanosine iupacName "(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy- 2-methyl-3,4-dihydro-1H-isoquinoline".
- Laudanosine thumbnail Laudanosine.svg?width=300.
- Laudanosine wikiPageID "14863278".
- Laudanosine wikiPageLength "4656".
- Laudanosine wikiPageOutDegree "23".
- Laudanosine wikiPageRevisionID "639245684".
- Laudanosine wikiPageWikiLink Alkaloid.
- Laudanosine wikiPageWikiLink Atracurium.
- Laudanosine wikiPageWikiLink Atracurium_besilate.
- Laudanosine wikiPageWikiLink Benzodiazepine_receptor.
- Laudanosine wikiPageWikiLink Benzyltetrahydroisoquinoline.
- Laudanosine wikiPageWikiLink Category:Convulsants.
- Laudanosine wikiPageWikiLink Category:GABAA_receptor_negative_allosteric_modulators.
- Laudanosine wikiPageWikiLink Category:Glycine_receptor_antagonists.
- Laudanosine wikiPageWikiLink Category:Natural_opium_alkaloids.
- Laudanosine wikiPageWikiLink Category:Nicotinic_antagonists.
- Laudanosine wikiPageWikiLink Category:Phenol_ethers.
- Laudanosine wikiPageWikiLink Category:Tetrahydroisoquinolines.
- Laudanosine wikiPageWikiLink Cisatracurium.
- Laudanosine wikiPageWikiLink Cisatracurium_besilate.
- Laudanosine wikiPageWikiLink Dehydration_reaction.
- Laudanosine wikiPageWikiLink GABAA_receptor.
- Laudanosine wikiPageWikiLink GABA_receptor.
- Laudanosine wikiPageWikiLink Glycine_receptor.
- Laudanosine wikiPageWikiLink Muscarinic_acetylcholine_receptor.
- Laudanosine wikiPageWikiLink Muscarinic_receptor.
- Laudanosine wikiPageWikiLink Nicotinic_acetylcholine_receptor.
- Laudanosine wikiPageWikiLink Opioid_receptor.
- Laudanosine wikiPageWikiLink Opium.
- Laudanosine wikiPageWikiLink Papaverine.
- Laudanosine wikiPageWikiLink File:Slaapbol_R0017601.JPG.
- Laudanosine wikiPageWikiLinkText "Laudanosine".
- Laudanosine wikiPageWikiLinkText "laudanosine".
- Laudanosine hasPhotoCollection Laudanosine.
- Laudanosine imagefile "Laudanosine.svg".
- Laudanosine iupacname "-1".
- Laudanosine othernames "N-Methyl-1,2,3,4-tetrahydropapaverine".
- Laudanosine verifiedfields "changed".
- Laudanosine verifiedrevid "424953216".
- Laudanosine watchedfields "changed".
- Laudanosine wikiPageUsesTemplate Template:Chembox.
- Laudanosine wikiPageUsesTemplate Template:Cholinergics.
- Laudanosine wikiPageUsesTemplate Template:GABAergics.
- Laudanosine wikiPageUsesTemplate Template:Glycinergics.
- Laudanosine wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Laudanosine wikiPageUsesTemplate Template:Opioidergics.
- Laudanosine wikiPageUsesTemplate Template:Reflist.
- Laudanosine subject Category:Convulsants.
- Laudanosine subject Category:GABAA_receptor_negative_allosteric_modulators.
- Laudanosine subject Category:Glycine_receptor_antagonists.
- Laudanosine subject Category:Natural_opium_alkaloids.
- Laudanosine subject Category:Nicotinic_antagonists.
- Laudanosine subject Category:Phenol_ethers.
- Laudanosine subject Category:Tetrahydroisoquinolines.
- Laudanosine hypernym Metabolite.
- Laudanosine type Article.
- Laudanosine type ChemicalCompound.
- Laudanosine type ChemicalSubstance.
- Laudanosine type Alkaloid.
- Laudanosine type Article.
- Laudanosine type Chemical.
- Laudanosine type Ether.
- Laudanosine type Heterocycle.
- Laudanosine type ChemicalObject.
- Laudanosine type Thing.
- Laudanosine type Q11173.
- Laudanosine comment "Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium.".
- Laudanosine label "Laudanosine".
- Laudanosine sameAs Laudanosin.
- Laudanosine sameAs Laudanosina.
- Laudanosine sameAs لودانوزین.
- Laudanosine sameAs m.03g_k_5.
- Laudanosine sameAs Laudanozin.
- Laudanosine sameAs Laudanozin.
- Laudanosine sameAs Q408074.
- Laudanosine sameAs Q408074.
- Laudanosine wasDerivedFrom Laudanosine?oldid=639245684.
- Laudanosine depiction Laudanosine.svg.
- Laudanosine isPrimaryTopicOf Laudanosine.