Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/JWH-007> ?p ?o }
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- JWH-007 abstract "JWH-007 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It was the most active of the first group of N-alkyl naphoylindoles discovered by the team led by John W Huffman, several years after the family was initially described with the discovery of the N-morpholinylethyl compounds pravadoline (WIN 48,098), WIN 55,225 (JWH-200) and WIN 55,212-2 by the Sterling Winthrop group. Several other N-alkyl substituents were found to be active by Huffman's team including the n-butyl, n-hexyl, 2-heptyl and cyclohexylethyl groups, but it was subsequently determined that the 2-methyl group on the indole ring is not required for CB1 binding, and tends to increase affinity for CB2 instead. Consequently the 2-desmethyl derivative of JWH-007, JWH-018 has slightly higher binding affinity for CB1, with an optimum binding of 9.00nM at CB1 and 2.94nM at CB2, and JWH-007 displayed optimum binding of 9.50nM at CB1 and 2.94nM at CB2.".
- JWH-007 casNumber "155471-10-6".
- JWH-007 iupacName "1-pentyl-2-methyl-3-(1-naphthoyl)indole".
- JWH-007 pubchem "10360860".
- JWH-007 thumbnail JWH-007_structure.png?width=300.
- JWH-007 wikiPageID "26653379".
- JWH-007 wikiPageLength "5916".
- JWH-007 wikiPageOutDegree "30".
- JWH-007 wikiPageRevisionID "683540130".
- JWH-007 wikiPageWikiLink Alkane.
- JWH-007 wikiPageWikiLink Alkyl.
- JWH-007 wikiPageWikiLink Analgesic.
- JWH-007 wikiPageWikiLink Butyl.
- JWH-007 wikiPageWikiLink Cannabinoid.
- JWH-007 wikiPageWikiLink Cannabinoid_receptor_1.
- JWH-007 wikiPageWikiLink Cannabinoid_receptor_2.
- JWH-007 wikiPageWikiLink Cannabinoid_receptor_type_1.
- JWH-007 wikiPageWikiLink Cannabinoid_receptor_type_2.
- JWH-007 wikiPageWikiLink Category:Designer_drugs.
- JWH-007 wikiPageWikiLink Category:JWH_cannabinoids.
- JWH-007 wikiPageWikiLink Category:Naphthoylindoles.
- JWH-007 wikiPageWikiLink Cyclohexane.
- JWH-007 wikiPageWikiLink Cyclohexyl.
- JWH-007 wikiPageWikiLink Desmethyl.
- JWH-007 wikiPageWikiLink Dissociation_constant.
- JWH-007 wikiPageWikiLink Ethyl_group.
- JWH-007 wikiPageWikiLink Heptyl.
- JWH-007 wikiPageWikiLink Hexyl.
- JWH-007 wikiPageWikiLink Indole.
- JWH-007 wikiPageWikiLink JWH-015.
- JWH-007 wikiPageWikiLink JWH-018.
- JWH-007 wikiPageWikiLink JWH-019.
- JWH-007 wikiPageWikiLink JWH-073.
- JWH-007 wikiPageWikiLink JWH-200.
- JWH-007 wikiPageWikiLink John_W._Huffman.
- JWH-007 wikiPageWikiLink John_W_Huffman.
- JWH-007 wikiPageWikiLink List_of_JWH_cannabinoids.
- JWH-007 wikiPageWikiLink Naphthoylindole.
- JWH-007 wikiPageWikiLink Poland.
- JWH-007 wikiPageWikiLink Pravadoline.
- JWH-007 wikiPageWikiLink Sterling_Drug.
- JWH-007 wikiPageWikiLink Sterling_Winthrop.
- JWH-007 wikiPageWikiLink Synthetic_cannabis.
- JWH-007 wikiPageWikiLink WIN_55,212-2.
- JWH-007 wikiPageWikiLinkText "JWH-007".
- JWH-007 c "25".
- JWH-007 casNumber "155471".
- JWH-007 chemspiderid "8536309".
- JWH-007 h "25".
- JWH-007 hasPhotoCollection JWH-007.
- JWH-007 inchi "1".
- JWH-007 inchikey "IBBNKINXTRKICJ-UHFFFAOYAJ".
- JWH-007 iupacName "1".
- JWH-007 molecularWeight "355.471".
- JWH-007 n "1".
- JWH-007 o "1".
- JWH-007 pubchem "10360860".
- JWH-007 smiles "c14ccccc4cccc1Cc3c2ccccc2nCCCCC".
- JWH-007 stdinchi "1".
- JWH-007 stdinchikey "IBBNKINXTRKICJ-UHFFFAOYSA-N".
- JWH-007 verifiedrevid "451554740".
- JWH-007 wikiPageUsesTemplate Template:Cannabinoid-stub.
- JWH-007 wikiPageUsesTemplate Template:Cannabinoids.
- JWH-007 wikiPageUsesTemplate Template:Drugbox.
- JWH-007 subject Category:Designer_drugs.
- JWH-007 subject Category:JWH_cannabinoids.
- JWH-007 subject Category:Naphthoylindoles.
- JWH-007 hypernym Chemical.
- JWH-007 type Article.
- JWH-007 type ChemicalCompound.
- JWH-007 type ChemicalSubstance.
- JWH-007 type Drug.
- JWH-007 type Article.
- JWH-007 type Cannabinoid.
- JWH-007 type Chemical.
- JWH-007 type Drug.
- JWH-007 type Ketone.
- JWH-007 type ChemicalObject.
- JWH-007 type Thing.
- JWH-007 type Q8386.
- JWH-007 comment "JWH-007 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It was the most active of the first group of N-alkyl naphoylindoles discovered by the team led by John W Huffman, several years after the family was initially described with the discovery of the N-morpholinylethyl compounds pravadoline (WIN 48,098), WIN 55,225 (JWH-200) and WIN 55,212-2 by the Sterling Winthrop group.".
- JWH-007 label "JWH-007".
- JWH-007 sameAs JWH-007.
- JWH-007 sameAs m.0bh79jr.
- JWH-007 sameAs JWH-007.
- JWH-007 sameAs JWH-007.
- JWH-007 sameAs Q6109172.
- JWH-007 sameAs Q6109172.
- JWH-007 wasDerivedFrom JWH-007?oldid=683540130.
- JWH-007 depiction JWH-007_structure.png.
- JWH-007 isPrimaryTopicOf JWH-007.