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- Isoprostane abstract "The isoprostanes are prostaglandin-like compounds formed in vivo from the free radical-catalyzed peroxidationof essential fatty acids (primarily arachidonic acid) without the direct action of cyclooxygenase (COX) enzymes. The compounds were discovered in 1990 by L. Jackson Roberts and Jason D. Morrow in the Division of Clinical Pharmacology at Vanderbilt University.These nonclassical eicosanoids possess potent biological activity as inflammatory mediators that augment the perception of pain. These compounds are accurate markers of lipid peroxidation in both animal and human models of oxidative stress.Elevated levels of isoprostanes are suspected of contributing to increased risk of heart attack in patients taking Coxibs. Isoprostanes and their metabolites have also been shown to be elevated in the urine of cigarette smokers, and have been suggested as biomarkers of oxidative stress in smokers.".
- Isoprostane wikiPageID "8778898".
- Isoprostane wikiPageLength "4672".
- Isoprostane wikiPageOutDegree "17".
- Isoprostane wikiPageRevisionID "678931534".
- Isoprostane wikiPageWikiLink Arachidonic_acid.
- Isoprostane wikiPageWikiLink COX-2_inhibitor.
- Isoprostane wikiPageWikiLink Category:Prostaglandins.
- Isoprostane wikiPageWikiLink Coxibs.
- Isoprostane wikiPageWikiLink Cyclooxygenase.
- Isoprostane wikiPageWikiLink Docosahexaenoic_acid.
- Isoprostane wikiPageWikiLink Eicosapentaenoic_acid.
- Isoprostane wikiPageWikiLink Essential_fatty_acid.
- Isoprostane wikiPageWikiLink Inflammation.
- Isoprostane wikiPageWikiLink Lipid_peroxidation.
- Isoprostane wikiPageWikiLink Neuroprostanes.
- Isoprostane wikiPageWikiLink Nonclassic_eicosanoid.
- Isoprostane wikiPageWikiLink Nonclassical_eicosanoid.
- Isoprostane wikiPageWikiLink Oxidative_stress.
- Isoprostane wikiPageWikiLink Pain.
- Isoprostane wikiPageWikiLink Prostaglandin.
- Isoprostane wikiPageWikiLinkText "8-isoprostane".
- Isoprostane wikiPageWikiLinkText "Isoprostane".
- Isoprostane wikiPageWikiLinkText "isoprostane".
- Isoprostane hasPhotoCollection Isoprostane.
- Isoprostane wikiPageUsesTemplate Template:Biochem-stub.
- Isoprostane wikiPageUsesTemplate Template:Citation_needed.
- Isoprostane subject Category:Prostaglandins.
- Isoprostane hypernym Compounds.
- Isoprostane type Article.
- Isoprostane type ChemicalCompound.
- Isoprostane type Article.
- Isoprostane type Eicosanoid.
- Isoprostane comment "The isoprostanes are prostaglandin-like compounds formed in vivo from the free radical-catalyzed peroxidationof essential fatty acids (primarily arachidonic acid) without the direct action of cyclooxygenase (COX) enzymes. The compounds were discovered in 1990 by L. Jackson Roberts and Jason D. Morrow in the Division of Clinical Pharmacology at Vanderbilt University.These nonclassical eicosanoids possess potent biological activity as inflammatory mediators that augment the perception of pain.".
- Isoprostane label "Isoprostane".
- Isoprostane sameAs m.027jfqz.
- Isoprostane sameAs Изопростаны.
- Isoprostane sameAs Q4198767.
- Isoprostane sameAs Q4198767.
- Isoprostane wasDerivedFrom Isoprostane?oldid=678931534.
- Isoprostane isPrimaryTopicOf Isoprostane.