Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Internalin> ?p ?o }
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- Internalin abstract "Internalins are surface proteins found on Listeria monocytogenes. They exist in two known forms, InlA and InlB. They are used by the bacteria to invade mammalian cells via cadherins transmembrane proteins and Met receptors respectively. The exact role of these proteins and their invasiveness in vivo is not completely understood. In cultured cells, InlA is necessary to facilitate Listeria entry into human epithelial cells. While InlB is necessary for Listeria internalisation in several other cell types, including hepatocytes, fibroblasts, and epithelioid cells. Internalins are mainly surface-exposed virulencefactors present in a number of Gram-positive bacteria whose role ranges from recognition of cellular receptors to aid in pathogen entry to escape from autophagy.Listeria possess a particular threat to pregnant women because of its ability to cross the placental blood barrier through the combined binding of both InIA and InIB to host cells. Research has shown that only the combined binding of these two virulence factors allows the bacteria to cross that barrier. This is not the case in mice and guinea pigs whose cells only have affinity for InIB in mice and InIA in guinea pigs.".
- Internalin wikiPageID "16537907".
- Internalin wikiPageLength "2385".
- Internalin wikiPageOutDegree "9".
- Internalin wikiPageRevisionID "645822403".
- Internalin wikiPageWikiLink C-Met.
- Internalin wikiPageWikiLink Cadherin.
- Internalin wikiPageWikiLink Category:Bacterial_proteins.
- Internalin wikiPageWikiLink Category:Virulence_factors.
- Internalin wikiPageWikiLink Fibroblast.
- Internalin wikiPageWikiLink Hepatocyte.
- Internalin wikiPageWikiLink Listeria_monocytogenes.
- Internalin wikiPageWikiLink Pascale_Cossart.
- Internalin wikiPageWikiLinkText "Internalin".
- Internalin wikiPageWikiLinkText "internalin".
- Internalin hasPhotoCollection Internalin.
- Internalin wikiPageUsesTemplate Template:Cell-biology-stub.
- Internalin wikiPageUsesTemplate Template:Reflist.
- Internalin subject Category:Bacterial_proteins.
- Internalin subject Category:Virulence_factors.
- Internalin hypernym Proteins.
- Internalin type Protein.
- Internalin comment "Internalins are surface proteins found on Listeria monocytogenes. They exist in two known forms, InlA and InlB. They are used by the bacteria to invade mammalian cells via cadherins transmembrane proteins and Met receptors respectively. The exact role of these proteins and their invasiveness in vivo is not completely understood. In cultured cells, InlA is necessary to facilitate Listeria entry into human epithelial cells.".
- Internalin label "Internalin".
- Internalin sameAs m.03y9f11.
- Internalin sameAs Q6047954.
- Internalin sameAs Q6047954.
- Internalin wasDerivedFrom Internalin?oldid=645822403.
- Internalin isPrimaryTopicOf Internalin.