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- Haematoxylin abstract "Haematoxylin, hematoxylin, Natural Black 1, or C.I. 75290 is a compound extracted from the heartwood of the logwood tree. Hematoxylin is a basic / positive compound that binds to and forms salts with acidic, or basophilic, compounds containing negative charges (such as DNA and RNA which are acidic/negative because the nucleic acid building blocks that come off the phosphate backbone are negatively charged) and stains them dark blue or violet. Haematoxylin and eosin together make up haematoxylin and eosin stain, one of the most commonly used stains in histology. This type of stain is a permanent stain as opposed to temporary stains (e.g. iodine solution in KI). Another common stain is phosphotungstic acid haematoxylin, a mix of haematoxylin with phosphotungstic acid. When oxidized it forms haematein, a compound that forms strongly coloured complexes with certain metal ions, the most notable ones being Fe(III) and Al(III) salts. Metal-haematein complexes are used to stain cell nuclei prior to examination under a microscope. Structures that stain with iron- or aluminium-haematein are often called basophilic, even though the mechanism of the staining is different from that of staining with basic dyes.In the early 1970s and in 2008, there were shortages of haematoxylin due to interruptions in its extraction from logwood. The price of the compound increased, affecting the cost of diagnostic histopathology, and prompted a search for alternative nuclear stains. Before the use of any alternatives became firmly established, haematoxylin returned to the market, though at a higher price, and resumed its place in histopathology. Several synthetic dyes have been recommended as replacements, notably celestine blue (CI 51050), gallocyanine (CI 51030), gallein (CI 45445) and eriochrome cyanine R (also called chromoxane cyanine R and solochrome cyanine (CI 43820). All four have Fe(III) as the mordant. Another alternative is the aluminium complex of oxidized brazilin, which differs from haematoxylin by only one hydroxyl group.".
- Haematoxylin iupacName "7,11b-Dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol".
- Haematoxylin thumbnail Hämatoxylin.svg?width=300.
- Haematoxylin wikiPageExternalLink 75290.htm.
- Haematoxylin wikiPageExternalLink JPCS_1_05.pdf.
- Haematoxylin wikiPageID "97726".
- Haematoxylin wikiPageLength "7927".
- Haematoxylin wikiPageOutDegree "36".
- Haematoxylin wikiPageRevisionID "665667902".
- Haematoxylin wikiPageWikiLink Alum.
- Haematoxylin wikiPageWikiLink Basic_dyes.
- Haematoxylin wikiPageWikiLink Basophilic.
- Haematoxylin wikiPageWikiLink Brazilin.
- Haematoxylin wikiPageWikiLink Category:Catechols.
- Haematoxylin wikiPageWikiLink Category:Natural_dyes.
- Haematoxylin wikiPageWikiLink Category:Phenol_dyes.
- Haematoxylin wikiPageWikiLink Category:Polyphenols.
- Haematoxylin wikiPageWikiLink Category:Staining_dyes.
- Haematoxylin wikiPageWikiLink Category:Tertiary_alcohols.
- Haematoxylin wikiPageWikiLink Celestine_blue.
- Haematoxylin wikiPageWikiLink Eosin.
- Haematoxylin wikiPageWikiLink Eriochrome_cyanine_R.
- Haematoxylin wikiPageWikiLink Gallein.
- Haematoxylin wikiPageWikiLink Gallocyanine.
- Haematoxylin wikiPageWikiLink H&E_stain.
- Haematoxylin wikiPageWikiLink Haematein.
- Haematoxylin wikiPageWikiLink Haematoxylum_campechianum.
- Haematoxylin wikiPageWikiLink Hematein.
- Haematoxylin wikiPageWikiLink Histology.
- Haematoxylin wikiPageWikiLink Histopathology.
- Haematoxylin wikiPageWikiLink Iron.
- Haematoxylin wikiPageWikiLink Logwood.
- Haematoxylin wikiPageWikiLink Microscope.
- Haematoxylin wikiPageWikiLink Mordant.
- Haematoxylin wikiPageWikiLink Phosphotungstic_acid.
- Haematoxylin wikiPageWikiLink Phosphotungstic_acid-haematoxylin_stain.
- Haematoxylin wikiPageWikiLink Phosphotungstic_acid_haematoxylin.
- Haematoxylin wikiPageWikiLink Redox.
- Haematoxylin wikiPageWikiLink Staining.
- Haematoxylin wikiPageWikiLink Staining_(biology).
- Haematoxylin wikiPageWikiLink Verhoeff’s_Stain.
- Haematoxylin wikiPageWikiLink Verhoeff’s_stain.
- Haematoxylin wikiPageWikiLink File:H&E_Eby_Loyola_University_Chicago.tif.
- Haematoxylin wikiPageWikiLink File:Haematein.png.
- Haematoxylin wikiPageWikiLinkText "Haematoxylin".
- Haematoxylin wikiPageWikiLinkText "haematoxylin".
- Haematoxylin wikiPageWikiLinkText "hematoxylin".
- Haematoxylin hasPhotoCollection Haematoxylin.
- Haematoxylin imagealt "Ball-and-stick model of the haematoxylin molecule".
- Haematoxylin imagealt "Skeletal formula of haematoxylin".
- Haematoxylin imagefile "Haematoxylin 3D ball.png".
- Haematoxylin imagefile "Hämatoxylin.svg".
- Haematoxylin imagesize "180".
- Haematoxylin imagesize "220".
- Haematoxylin iupacname "711".
- Haematoxylin othernames "Hematoxylin; Natural Black 1; Hematoxyline; Hydroxybrazilin; Hydroxybrasilin; C.I. 75290".
- Haematoxylin verifiedfields "changed".
- Haematoxylin verifiedrevid "446217709".
- Haematoxylin watchedfields "changed".
- Haematoxylin wikiPageUsesTemplate Template:Chembox.
- Haematoxylin wikiPageUsesTemplate Template:Nofootnotes.
- Haematoxylin wikiPageUsesTemplate Template:Reflist.
- Haematoxylin wikiPageUsesTemplate Template:Stains.
- Haematoxylin subject Category:Catechols.
- Haematoxylin subject Category:Natural_dyes.
- Haematoxylin subject Category:Phenol_dyes.
- Haematoxylin subject Category:Polyphenols.
- Haematoxylin subject Category:Staining_dyes.
- Haematoxylin subject Category:Tertiary_alcohols.
- Haematoxylin hypernym Compound.
- Haematoxylin type Article.
- Haematoxylin type ChemicalCompound.
- Haematoxylin type ChemicalSubstance.
- Haematoxylin type Alcohol.
- Haematoxylin type Article.
- Haematoxylin type Heterocycle.
- Haematoxylin type ChemicalObject.
- Haematoxylin type Thing.
- Haematoxylin type Q11173.
- Haematoxylin comment "Haematoxylin, hematoxylin, Natural Black 1, or C.I. 75290 is a compound extracted from the heartwood of the logwood tree. Hematoxylin is a basic / positive compound that binds to and forms salts with acidic, or basophilic, compounds containing negative charges (such as DNA and RNA which are acidic/negative because the nucleic acid building blocks that come off the phosphate backbone are negatively charged) and stains them dark blue or violet.".
- Haematoxylin label "Haematoxylin".
- Haematoxylin sameAs Hematoxilina.
- Haematoxylin sameAs Hematoxylin.
- Haematoxylin sameAs Hämatoxylin.
- Haematoxylin sameAs Hematoxilina.
- Haematoxylin sameAs هایماتوزیلین.
- Haematoxylin sameAs Hematoxilina.
- Haematoxylin sameAs Ematossilina.
- Haematoxylin sameAs ヘマトキシリン.
- Haematoxylin sameAs Гематоксилин.
- Haematoxylin sameAs Hematoksylina.
- Haematoxylin sameAs Hematoxilina.
- Haematoxylin sameAs m.0p4t0.
- Haematoxylin sameAs Hematoxilină.
- Haematoxylin sameAs Гематоксилин.
- Haematoxylin sameAs Haematoksilin.
- Haematoxylin sameAs Hematoxylín.
- Haematoxylin sameAs Hematoksilin.
- Haematoxylin sameAs Haematoksilin.
- Haematoxylin sameAs Hematoksilin.