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- Fadogia_homblei abstract "Fadogia homblei De Wild. is a 60 cm tall erect perennial Sub-Saharan shrublet with subterranean stems producing unbranched annual shoots, and is one of some 47 species of Fadogia belonging to the family of Rubiaceae. It occurs in Angola, Tanzania, Malawi, Mozambique, Zambia, Zimbabwe, and in Limpopo and Gauteng Provinces in South Africa.This species has leaves in whorls of 3-5. The leaves are elliptic or lanceolate, shiny above, with greyish-white papillose hairs on the undersurface. Fragrant flowers are in 3-5-flowered whorls arising from the leaf nodes, and are creamy yellow to bright yellow in colour. The fruit is spherical, crowned with the persistent calyx limb, initially green, but turning black when ripe, and is edible.Browsing of this species has long been known to cause 'gousiekte' ("quick disease"), a cardiotoxicosis of ruminants marked by heart failure four to eight weeks after ingestion of certain species of Vangueria, Pavetta and Fadogia, and is thought to be caused by the polyamine, pavettamine. All six plants known to cause gousiekte are members of the Rubiaceae family. Laboratory analysis revealed that the pavettamine concentration in Fadogia homblei was highest in the topmost leaf pair, and decreased towards the base of the plant. All the gousiekte-causing plants have symbiotic bacteria in their leaves, and at first these were suspected of playing a role in the production of pavettamine. However cultures of the bacteria have not revealed any traces of pavettamine, showing that the toxin is either from an interaction with the plant or solely produced by the plant. The structure of pavettamine remained elusive, but was finally published in 2010 by Bode et al., some 15 years after it was first isolated, and found to be (2S,4R,8R,10S)-1,11-diamino-6-aza-undecane-2,4,8,10-tetraol. Despite the determination of pavettamine's structure it has yet to be linked to gousiekte.A large number of compounds were isolated from the fruits, leaves and stem of the species, including:Scopoletin anti-fungal, anti-spasmodic, anti-oxidant, anti-inflammatory and anti-cancer. Luteolin anti-mutagenic, anti-tumor, anti-oxidant and anti-inflammatory. Quercetin 3-O-β-D-galactoside is common in plants and an active ingredient of many herbal remedies, anti-hypertensive, vasodilatory. Lupeol anti-oxidant, anti-angiogenic, anti-neoplastic, anti-inflammatory and anti-malarial. Betulinic acid anti-inflammatory, in vitro anti-malarial, anti-HIV and anti-cancer. Sitosterol and stigmasterol common compounds found in almost all plant species.Pinoresinol inhibitor of 15-lipoxygenase.Uracil was isolated from the leaf of Fadogia homblei, significant as the first finding of uracil from plants other than ferns.↑ ↑ ↑ ↑ ↑".
- Fadogia_homblei binomialAuthority Émile_Auguste_Joseph_De_Wildeman.
- Fadogia_homblei class Eudicots.
- Fadogia_homblei division Flowering_plant.
- Fadogia_homblei family Rubiaceae.
- Fadogia_homblei genus Fadogia.
- Fadogia_homblei kingdom Plant.
- Fadogia_homblei order Asterids.
- Fadogia_homblei order Gentianales.
- Fadogia_homblei thumbnail Fadogia_homblei01.jpg?width=300.
- Fadogia_homblei wikiPageID "41668274".
- Fadogia_homblei wikiPageLength "3982".
- Fadogia_homblei wikiPageOutDegree "35".
- Fadogia_homblei wikiPageRevisionID "638099094".
- Fadogia_homblei wikiPageWikiLink Angiosperms.
- Fadogia_homblei wikiPageWikiLink Angola.
- Fadogia_homblei wikiPageWikiLink Asterids.
- Fadogia_homblei wikiPageWikiLink Beta-Sitosterol.
- Fadogia_homblei wikiPageWikiLink Betulinic_acid.
- Fadogia_homblei wikiPageWikiLink Category:Fadogia.
- Fadogia_homblei wikiPageWikiLink Category:Flora_of_Africa.
- Fadogia_homblei wikiPageWikiLink De_Wild..
- Fadogia_homblei wikiPageWikiLink Eudicots.
- Fadogia_homblei wikiPageWikiLink Fadogia.
- Fadogia_homblei wikiPageWikiLink Flowering_plant.
- Fadogia_homblei wikiPageWikiLink Gentianales.
- Fadogia_homblei wikiPageWikiLink Lupeol.
- Fadogia_homblei wikiPageWikiLink Luteolin.
- Fadogia_homblei wikiPageWikiLink Malawi.
- Fadogia_homblei wikiPageWikiLink Mozambique.
- Fadogia_homblei wikiPageWikiLink Pavetta.
- Fadogia_homblei wikiPageWikiLink Pinoresinol.
- Fadogia_homblei wikiPageWikiLink Plant.
- Fadogia_homblei wikiPageWikiLink Plantae.
- Fadogia_homblei wikiPageWikiLink Polyamine.
- Fadogia_homblei wikiPageWikiLink Quercetin.
- Fadogia_homblei wikiPageWikiLink Rubiaceae.
- Fadogia_homblei wikiPageWikiLink Ruminant.
- Fadogia_homblei wikiPageWikiLink Ruminants.
- Fadogia_homblei wikiPageWikiLink Scopoletin.
- Fadogia_homblei wikiPageWikiLink Sitosterol.
- Fadogia_homblei wikiPageWikiLink South_Africa.
- Fadogia_homblei wikiPageWikiLink Stigmasterol.
- Fadogia_homblei wikiPageWikiLink Sub-Saharan.
- Fadogia_homblei wikiPageWikiLink Sub-Saharan_Africa.
- Fadogia_homblei wikiPageWikiLink Tanzania.
- Fadogia_homblei wikiPageWikiLink Uracil.
- Fadogia_homblei wikiPageWikiLink Vangueria.
- Fadogia_homblei wikiPageWikiLink Zambia.
- Fadogia_homblei wikiPageWikiLink Zimbabwe.
- Fadogia_homblei wikiPageWikiLink Émile_Auguste_Joseph_De_Wildeman.
- Fadogia_homblei wikiPageWikiLink File:Fadogia_homblei02.jpg.
- Fadogia_homblei wikiPageWikiLinkText "Fadogia homblei".
- Fadogia_homblei binomial "Fadogia homblei".
- Fadogia_homblei binomialAuthority De_Wild..
- Fadogia_homblei binomialAuthority Émile_Auguste_Joseph_De_Wildeman.
- Fadogia_homblei familia Rubiaceae.
- Fadogia_homblei genus "Fadogia".
- Fadogia_homblei hasPhotoCollection Fadogia_homblei.
- Fadogia_homblei ordo Gentianales.
- Fadogia_homblei regnum Plant.
- Fadogia_homblei regnum Plantae.
- Fadogia_homblei species "F. homblei".
- Fadogia_homblei unrankedClassis Eudicots.
- Fadogia_homblei unrankedDivisio Angiosperms.
- Fadogia_homblei unrankedDivisio Flowering_plant.
- Fadogia_homblei unrankedOrdo Asterids.
- Fadogia_homblei wikiPageUsesTemplate Template:AfricanPlants.
- Fadogia_homblei wikiPageUsesTemplate Template:Italic_title.
- Fadogia_homblei wikiPageUsesTemplate Template:Reflist.
- Fadogia_homblei wikiPageUsesTemplate Template:Taxobox.
- Fadogia_homblei subject Category:Fadogia.
- Fadogia_homblei subject Category:Flora_of_Africa.
- Fadogia_homblei type Eukaryote.
- Fadogia_homblei type Plant.
- Fadogia_homblei type Species.
- Fadogia_homblei type Thing.
- Fadogia_homblei type Q19088.
- Fadogia_homblei type Q756.
- Fadogia_homblei comment "Fadogia homblei De Wild. is a 60 cm tall erect perennial Sub-Saharan shrublet with subterranean stems producing unbranched annual shoots, and is one of some 47 species of Fadogia belonging to the family of Rubiaceae. It occurs in Angola, Tanzania, Malawi, Mozambique, Zambia, Zimbabwe, and in Limpopo and Gauteng Provinces in South Africa.This species has leaves in whorls of 3-5. The leaves are elliptic or lanceolate, shiny above, with greyish-white papillose hairs on the undersurface.".
- Fadogia_homblei label "Fadogia homblei".
- Fadogia_homblei sameAs Fadogia_homblei.
- Fadogia_homblei sameAs m.0_86vq5.
- Fadogia_homblei sameAs Fadogia_homblei.
- Fadogia_homblei sameAs Fadogia_homblei.
- Fadogia_homblei sameAs Fadogia_homblei.
- Fadogia_homblei sameAs Q15442419.
- Fadogia_homblei sameAs Q15442419.
- Fadogia_homblei wasDerivedFrom Fadogia_homblei?oldid=638099094.
- Fadogia_homblei depiction Fadogia_homblei01.jpg.
- Fadogia_homblei isPrimaryTopicOf Fadogia_homblei.