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- Erythromycin_breath_test abstract "The erythromycin breath test (ERMBT) is a method used to measure metabolism (oxidation and elimination from the system) by a part of the cytochrome P450 system. Erythromycin is tagged with carbon-14 and given as an intravenous injection; after 20 minutes the subject blows up a balloon and the carbon dioxide exhaled that is tagged with carbon-14 shows the activity of the CYP3A4 isoenzyme on the erythromycin. Therefore, this activity can predict how other drugs that are metabolized by the CYP3A4 part of the cytochrome P450 system will be acted upon by a particular person.This is important because it allows doctors to determine or predict an individual’s drug treatment outcome. Will a patient develop serious or fatal side effects from a certain drug? Which foods and drugs should not be taken together? With this and other tests a physician may determine treatment outcomes in advance or study the effects of new drugs.Some patients have a congenital inability to synthesize certain enzymes, so drugs may build up to toxic levels in their system or other drugs and foods a patient is taking may consume all of their ability to metabolize certain foods and drugs. An example is: when a person taking a cholesterol-lowering statin drug then drinking grapefruit juice, they may have a poor treatment outcome (adverse drug reaction) and sustain liver damage or kidney failure due to drug induced rhabdomyolysis (the breaking up of muscle tissue).".
- Erythromycin_breath_test wikiPageID "7301023".
- Erythromycin_breath_test wikiPageLength "1958".
- Erythromycin_breath_test wikiPageOutDegree "15".
- Erythromycin_breath_test wikiPageRevisionID "678800360".
- Erythromycin_breath_test wikiPageWikiLink Adverse_drug_reaction.
- Erythromycin_breath_test wikiPageWikiLink CYP3A4.
- Erythromycin_breath_test wikiPageWikiLink Carbon-14.
- Erythromycin_breath_test wikiPageWikiLink Carbon_dioxide.
- Erythromycin_breath_test wikiPageWikiLink Category:Breath_tests.
- Erythromycin_breath_test wikiPageWikiLink Category:Enzymes.
- Erythromycin_breath_test wikiPageWikiLink Congenital.
- Erythromycin_breath_test wikiPageWikiLink Congenital_disorder.
- Erythromycin_breath_test wikiPageWikiLink Cytochrome_P450.
- Erythromycin_breath_test wikiPageWikiLink Erythromycin.
- Erythromycin_breath_test wikiPageWikiLink Grapefruit_juice.
- Erythromycin_breath_test wikiPageWikiLink Isoenzyme.
- Erythromycin_breath_test wikiPageWikiLink Isotopic_labeling.
- Erythromycin_breath_test wikiPageWikiLink Isotopic_labelling.
- Erythromycin_breath_test wikiPageWikiLink Isozyme.
- Erythromycin_breath_test wikiPageWikiLink Metabolism.
- Erythromycin_breath_test wikiPageWikiLink Rhabdomyolysis.
- Erythromycin_breath_test wikiPageWikiLink Statin.
- Erythromycin_breath_test wikiPageWikiLinkText "erythromycin breath test".
- Erythromycin_breath_test hasPhotoCollection Erythromycin_breath_test.
- Erythromycin_breath_test wikiPageUsesTemplate Template:Reflist.
- Erythromycin_breath_test subject Category:Breath_tests.
- Erythromycin_breath_test subject Category:Enzymes.
- Erythromycin_breath_test hypernym Method.
- Erythromycin_breath_test type Software.
- Erythromycin_breath_test comment "The erythromycin breath test (ERMBT) is a method used to measure metabolism (oxidation and elimination from the system) by a part of the cytochrome P450 system. Erythromycin is tagged with carbon-14 and given as an intravenous injection; after 20 minutes the subject blows up a balloon and the carbon dioxide exhaled that is tagged with carbon-14 shows the activity of the CYP3A4 isoenzyme on the erythromycin.".
- Erythromycin_breath_test label "Erythromycin breath test".
- Erythromycin_breath_test sameAs m.025ym8x.
- Erythromycin_breath_test sameAs Q5396488.
- Erythromycin_breath_test sameAs Q5396488.
- Erythromycin_breath_test wasDerivedFrom Erythromycin_breath_test?oldid=678800360.
- Erythromycin_breath_test isPrimaryTopicOf Erythromycin_breath_test.