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- EC50 abstract "The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. It is commonly used as a measure of drug's potency.The EC50 of a graded dose response curve therefore represents the concentration of a compound where 50% of its maximal effect is observed. The EC50 of a quantal dose response curve represents the concentration of a compound where 50% of the population exhibit a response, after a specified exposure duration.It is also related to IC50 which is a measure of a compound's inhibition (50% inhibition). For competition binding assays and functional antagonist assays IC50 is the most common summary measure of the dose-response curve. For agonist/stimulator assays the most common summary measure is the EC50. Sometimes it is also expressed as pEC50 = - LOG(EC50) (with EC50 in M/l).A small change in ligand concentration typically result in rapid changes in response in the biological system, following a sigmoidal function.The inflection point at which the increase in response with increasing ligand concentration begins to slow is the EC50. Which can be mathematically determined by derivation of the best-fit line. While relying on a graph for estimation is more convenient, this typical method yields less accurate results and less precise.".
- EC50 wikiPageExternalLink 597.
- EC50 wikiPageExternalLink ec50.html.
- EC50 wikiPageExternalLink IC50.htm.
- EC50 wikiPageID "3742950".
- EC50 wikiPageLength "4064".
- EC50 wikiPageOutDegree "17".
- EC50 wikiPageRevisionID "678645516".
- EC50 wikiPageWikiLink Category:Pharmacodynamics.
- EC50 wikiPageWikiLink Category:Toxicology.
- EC50 wikiPageWikiLink Certain_safety_factor.
- EC50 wikiPageWikiLink Dose-response_relationship.
- EC50 wikiPageWikiLink Dose_response_curve.
- EC50 wikiPageWikiLink Dose–response_relationship.
- EC50 wikiPageWikiLink Hill_coefficient.
- EC50 wikiPageWikiLink Hill_equation_(biochemistry).
- EC50 wikiPageWikiLink IC50.
- EC50 wikiPageWikiLink Inflection_point.
- EC50 wikiPageWikiLink LD50.
- EC50 wikiPageWikiLink Ligand.
- EC50 wikiPageWikiLink Measures_of_pollutant_concentration.
- EC50 wikiPageWikiLink Median_lethal_dose.
- EC50 wikiPageWikiLink Potency_(pharmacology).
- EC50 wikiPageWikiLink Sigmoid_function.
- EC50 wikiPageWikiLink Therapeutic_index.
- EC50 wikiPageWikiLink Toxicity.
- EC50 wikiPageWikiLinkText "EC50".
- EC50 wikiPageWikiLinkText "half-maximal".
- EC50 hasPhotoCollection EC50.
- EC50 subject Category:Pharmacodynamics.
- EC50 subject Category:Toxicology.
- EC50 type Article.
- EC50 type Article.
- EC50 type Science.
- EC50 type Specialty.
- EC50 comment "The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. It is commonly used as a measure of drug's potency.The EC50 of a graded dose response curve therefore represents the concentration of a compound where 50% of its maximal effect is observed.".
- EC50 label "EC50".
- EC50 sameAs EC50.
- EC50 sameAs Concentration_efficace_médiane.
- EC50 sameAs EC50.
- EC50 sameAs EC50.
- EC50 sameAs EC50.
- EC50 sameAs m.09yld5.
- EC50 sameAs EC50.
- EC50 sameAs EC50.
- EC50 sameAs EC50.
- EC50 sameAs EC50.
- EC50 sameAs Q286136.
- EC50 sameAs Q286136.
- EC50 wasDerivedFrom EC50?oldid=678645516.
- EC50 isPrimaryTopicOf EC50.