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- Cinepazide abstract "Cinepazide or cinepazide maleate (Kelinao or Anjieli in China) is a vasodilator used in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases. It appears to work by potentiating A2 adenosine receptors.It was discovered by scientists at Laboratoires Delalande (now part of Sanofi) in 1969 in an effort to explore useful substituted cinnamoyl-piperazine compounds. The drug, in the form of a pill taken orally, was launched by Delalande in 1976 under the tradename Vasodistal, for treatment of heart failure, balance disorders, cerebrovascular disease, and vascular complications of diabetes. In 1988 the drug was withdrawn from the market in Spain due to risk of agranulocytosis; other countries where the drug was available added warnings to the label. It was withdrawn from the market in France in 1992. The drug had also been marketed in Japan by Daiichi under the brand name "Brindel" for dementia, but was withdrawn in 1999, following a review by the Japanese regulatory authorities of dementia drugs after a drug, calcium hopantenate, that had been considered the standard of care and against which cinepazide and other dementia drugs had been compared, had failed to demonstrate efficacy in a re-evaluation.In 2002 Sihuan Pharmaceutical brought an injectable form of the drug to market in China; Sihuan had acquired the drug from a military hospital in China that had developed the formulation. In 2010 it was the highest selling drug in China, with about 1 billion RMB in sales in the 3rd quarter, outselling Plavix in China. This made Sihuan Pharm the largest company in China in the cardio-cerebral vascular drug market in 2010. In 2014 it was the tenth highest-selling drug in China.".
- Cinepazide atcPrefix "C04".
- Cinepazide atcSuffix "AX27".
- Cinepazide fdaUniiCode "67Y4P5C84X".
- Cinepazide iupacName "1-{4-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one".
- Cinepazide pubchem "5282459".
- Cinepazide thumbnail Cinepazide.svg?width=300.
- Cinepazide wikiPageID "20799737".
- Cinepazide wikiPageLength "6562".
- Cinepazide wikiPageOutDegree "20".
- Cinepazide wikiPageRevisionID "677667751".
- Cinepazide wikiPageWikiLink Adenosine_receptor.
- Cinepazide wikiPageWikiLink Adenosine_receptors.
- Cinepazide wikiPageWikiLink Agranulocytosis.
- Cinepazide wikiPageWikiLink Balance_disorder.
- Cinepazide wikiPageWikiLink Balance_disorders.
- Cinepazide wikiPageWikiLink Calcium_hopantenate.
- Cinepazide wikiPageWikiLink Category:Amides.
- Cinepazide wikiPageWikiLink Category:Phenol_ethers.
- Cinepazide wikiPageWikiLink Category:Piperazines.
- Cinepazide wikiPageWikiLink Category:Pyrrolidines.
- Cinepazide wikiPageWikiLink Cerebrovascular_disease.
- Cinepazide wikiPageWikiLink Cerebrovascular_diseases.
- Cinepazide wikiPageWikiLink Cinnamic_acid.
- Cinepazide wikiPageWikiLink Cinnamoyl.
- Cinepazide wikiPageWikiLink Clopidogrel.
- Cinepazide wikiPageWikiLink Dai-ichi.
- Cinepazide wikiPageWikiLink Daiichi.
- Cinepazide wikiPageWikiLink Heart_failure.
- Cinepazide wikiPageWikiLink Peripheral_artery_disease.
- Cinepazide wikiPageWikiLink Peripheral_vascular_diseases.
- Cinepazide wikiPageWikiLink Piperazine.
- Cinepazide wikiPageWikiLink Plavix.
- Cinepazide wikiPageWikiLink Sanofi.
- Cinepazide wikiPageWikiLink Sihuan_Pharmaceutical.
- Cinepazide wikiPageWikiLink Vascular_disease.
- Cinepazide wikiPageWikiLink Vasodilation.
- Cinepazide wikiPageWikiLink Vasodilator.
- Cinepazide wikiPageWikiLinkText "Cinepazide".
- Cinepazide wikiPageWikiLinkText "cinepazide".
- Cinepazide atcPrefix "4.0".
- Cinepazide atcSuffix "AX27".
- Cinepazide c "22".
- Cinepazide chembl "1874750".
- Cinepazide chemspiderid "4445611".
- Cinepazide h "31".
- Cinepazide hasPhotoCollection Cinepazide.
- Cinepazide inchi "1".
- Cinepazide inchikey "RCUDFXMNPQNBDU-VOTSOKGWBJ".
- Cinepazide iupacName "1".
- Cinepazide molecularWeight "417.49864".
- Cinepazide n "3".
- Cinepazide o "5".
- Cinepazide pubchem "5282459".
- Cinepazide smiles "O=CCN3CCNCC3".
- Cinepazide stdinchi "1".
- Cinepazide stdinchikey "RCUDFXMNPQNBDU-VOTSOKGWSA-N".
- Cinepazide unii "67".
- Cinepazide verifiedrevid "447331147".
- Cinepazide watchedfields "changed".
- Cinepazide wikiPageUsesTemplate Template:Cardiovascular-drug-stub.
- Cinepazide wikiPageUsesTemplate Template:Drugbox.
- Cinepazide wikiPageUsesTemplate Template:Peripheral_vasodilators.
- Cinepazide wikiPageUsesTemplate Template:Reflist.
- Cinepazide subject Category:Amides.
- Cinepazide subject Category:Phenol_ethers.
- Cinepazide subject Category:Piperazines.
- Cinepazide subject Category:Pyrrolidines.
- Cinepazide hypernym Vasodilator.
- Cinepazide type Article.
- Cinepazide type ChemicalSubstance.
- Cinepazide type Drug.
- Cinepazide type Group.
- Cinepazide type Amide.
- Cinepazide type Article.
- Cinepazide type Chemical.
- Cinepazide type Drug.
- Cinepazide type Ether.
- Cinepazide type Group.
- Cinepazide type Heterocycle.
- Cinepazide type ChemicalObject.
- Cinepazide type Thing.
- Cinepazide type Q8386.
- Cinepazide comment "Cinepazide or cinepazide maleate (Kelinao or Anjieli in China) is a vasodilator used in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases. It appears to work by potentiating A2 adenosine receptors.It was discovered by scientists at Laboratoires Delalande (now part of Sanofi) in 1969 in an effort to explore useful substituted cinnamoyl-piperazine compounds.".
- Cinepazide label "Cinepazide".
- Cinepazide sameAs m.053m82z.
- Cinepazide sameAs Cinepazid.
- Cinepazide sameAs Cinepazid.
- Cinepazide sameAs Q5120864.
- Cinepazide sameAs Q5120864.
- Cinepazide wasDerivedFrom Cinepazide?oldid=677667751.
- Cinepazide depiction Cinepazide.svg.
- Cinepazide isPrimaryTopicOf Cinepazide.