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- Bioorthogonal_chemical_reporter abstract "In chemical biology, bioorthogonal chemical reporter is a non-native chemical functionality that is introduced into the naturally occurring biomolecules of a living system, generally through metabolic or protein engineering. These functional groups are subsequently utilized for tagging and visualizing biomolecules. Prescher & Carolyn R. Bertozzi, the developers of bioorthogonal chemistry, defined bioorthogonal chemical reporters as "non-native, non-perturbing chemical handles that can be modified in living systems through highly selective reactions with exogenously delivered probes." It has been used to enrich proteins and to conduct proteomic analysis.In the early development of the technique, chemical motifs have to fulfill criteria of biocompatibility and selective reactivity in order to qualify as bioorthogonal chemical reporters. Some combinations of proteinogenic amino acid side chains meet the criteria, as do ketones and aldehydes (which can tag proteins and some metabolites). Azides and alkynes are other examples of chemical reporters.A bioorthogonal chemical reporter must be incorporated into a biomolecule. This occurs via metabolism. The chemical reporter is linked to a substrate, which a cell can metabolize.".
- Bioorthogonal_chemical_reporter wikiPageID "2372394".
- Bioorthogonal_chemical_reporter wikiPageLength "1771".
- Bioorthogonal_chemical_reporter wikiPageOutDegree "28".
- Bioorthogonal_chemical_reporter wikiPageRevisionID "467619229".
- Bioorthogonal_chemical_reporter wikiPageWikiLink Aldehyde.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Alkyne.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Amino_acid.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Azide.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Biocompatibility.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Biomolecule.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Bioorthogonal_chemistry.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Carolyn_R._Bertozzi.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Category:Biochemistry_methods.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Cell_(biology).
- Bioorthogonal_chemical_reporter wikiPageWikiLink Chemical_biology.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Chemical_reaction.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Functional_group.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Ketone.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Living_system.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Living_systems.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Metabolism.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Nature_Chemical_Biology.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Protein.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Protein_engineering.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Proteinogenic.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Proteinogenic_amino_acid.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Proteomics.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Side_chain.
- Bioorthogonal_chemical_reporter wikiPageWikiLink Substrate_(chemistry).
- Bioorthogonal_chemical_reporter wikiPageWikiLinkText "Bioorthogonal chemical reporter".
- Bioorthogonal_chemical_reporter wikiPageWikiLinkText "chemical reporter".
- Bioorthogonal_chemical_reporter wikiPageWikiLinkText "chemical reporters".
- Bioorthogonal_chemical_reporter hasPhotoCollection Bioorthogonal_chemical_reporter.
- Bioorthogonal_chemical_reporter wikiPageUsesTemplate Template:Biochem-stub.
- Bioorthogonal_chemical_reporter wikiPageUsesTemplate Template:Cite_journal.
- Bioorthogonal_chemical_reporter subject Category:Biochemistry_methods.
- Bioorthogonal_chemical_reporter hypernym Functionality.
- Bioorthogonal_chemical_reporter type Software.
- Bioorthogonal_chemical_reporter type Method.
- Bioorthogonal_chemical_reporter type Technique.
- Bioorthogonal_chemical_reporter comment "In chemical biology, bioorthogonal chemical reporter is a non-native chemical functionality that is introduced into the naturally occurring biomolecules of a living system, generally through metabolic or protein engineering. These functional groups are subsequently utilized for tagging and visualizing biomolecules. Prescher & Carolyn R.".
- Bioorthogonal_chemical_reporter label "Bioorthogonal chemical reporter".
- Bioorthogonal_chemical_reporter sameAs m.07783z.
- Bioorthogonal_chemical_reporter sameAs Q4915200.
- Bioorthogonal_chemical_reporter sameAs Q4915200.
- Bioorthogonal_chemical_reporter wasDerivedFrom Bioorthogonal_chemical_reporter?oldid=467619229.
- Bioorthogonal_chemical_reporter isPrimaryTopicOf Bioorthogonal_chemical_reporter.