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- Accelerator_Prevention_Trial_(adAPT) abstract "Diabetes results from the loss or malfunction of the beta cells in the pancreas that make insulin. Autoimmunity has been the accepted explanation for type 1 diabetes (T1D) for 40 years, but clinical trials of immunotherapy have proved disappointing, and have not provided a means of prevention. The accelerator hypothesis proposes a different explanation for T1D, based on the tempo of beta cell loss and the environmental factors that drive it. The autoimmune diabetes Accelerator Prevention Trial (adAPT) is testing the accelerator hypothesis, by seeking to establish whether the drug metformin can slow the tempo sufficiently to reduce the incidence of diabetes in children at risk. The trial is sponsored by the University of Exeter, conducted in Scotland by the Tayside Clinical Trials Unit and funded by JDRF. It will report finally in 2022.".
- Accelerator_Prevention_Trial_(adAPT) wikiPageID "43528987".
- Accelerator_Prevention_Trial_(adAPT) wikiPageLength "7346".
- Accelerator_Prevention_Trial_(adAPT) wikiPageOutDegree "27".
- Accelerator_Prevention_Trial_(adAPT) wikiPageRevisionID "669288903".
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Accelerator_hypothesis.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Antibodies.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Antibody.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Autoimmunity.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Beta_cell.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Beta_cells.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink C-peptide.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Category:Diabetes.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Continuous_glucose_monitoring.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Diabetes.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Diabetes_mellitus.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Diabetes_mellitus_type_1.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Diabetes_mellitus_type_2.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink HLA.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink HOMA2-IR.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Homeostasis.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Homeostatic.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Insulinogenic_index.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink JDRF.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Juvenile_Diabetes_Research_Foundation.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Metformin.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Mixed_meal_tolerance_test.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Placebo.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Tayside_Clinical_Trials_Unit.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Tyneside.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Type_1_diabetes.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink Type_2_diabetes.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLink University_of_Exeter.
- Accelerator_Prevention_Trial_(adAPT) wikiPageWikiLinkText "Accelerator Prevention Trial (adAPT)".
- Accelerator_Prevention_Trial_(adAPT) hasPhotoCollection Accelerator_Prevention_Trial_(adAPT).
- Accelerator_Prevention_Trial_(adAPT) wikiPageUsesTemplate Template:Reflist.
- Accelerator_Prevention_Trial_(adAPT) subject Category:Diabetes.
- Accelerator_Prevention_Trial_(adAPT) comment "Diabetes results from the loss or malfunction of the beta cells in the pancreas that make insulin. Autoimmunity has been the accepted explanation for type 1 diabetes (T1D) for 40 years, but clinical trials of immunotherapy have proved disappointing, and have not provided a means of prevention. The accelerator hypothesis proposes a different explanation for T1D, based on the tempo of beta cell loss and the environmental factors that drive it.".
- Accelerator_Prevention_Trial_(adAPT) label "Accelerator Prevention Trial (adAPT)".
- Accelerator_Prevention_Trial_(adAPT) sameAs Q18350013.
- Accelerator_Prevention_Trial_(adAPT) sameAs Q18350013.
- Accelerator_Prevention_Trial_(adAPT) wasDerivedFrom Accelerator_Prevention_Trial_(adAPT)?oldid=669288903.
- Accelerator_Prevention_Trial_(adAPT) isPrimaryTopicOf Accelerator_Prevention_Trial_(adAPT).