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- Q8565284 subject Q7214254.
- Q8565284 subject Q7300121.
- Q8565284 abstract "Fragment-based lead discovery (FBLD) also known as fragment-based drug discovery (FBDD) is a method used for finding lead compounds as part of the drug discovery process. It is based on identifying small chemical fragments, which may bind only weakly to the biological target, and then growing them or combining them to produce a lead with a higher affinity. FBLD can be compared with high-throughput screening (HTS). In HTS, libraries with up to millions of compounds, with molecular weights of around 500 Da, are screened, and nanomolar binding affinities are sought. In contrast, in the early phase of FBLD, libraries with a few thousand compounds with molecular weights of around 200 Da may be screened, and millimolar affinities can be considered useful.".
- Q8565284 wikiPageWikiLink Q1418791.
- Q8565284 wikiPageWikiLink Q161064.
- Q8565284 wikiPageWikiLink Q169324.
- Q8565284 wikiPageWikiLink Q182854.
- Q8565284 wikiPageWikiLink Q45003.
- Q8565284 wikiPageWikiLink Q483261.
- Q8565284 wikiPageWikiLink Q5308941.
- Q8565284 wikiPageWikiLink Q5318955.
- Q8565284 wikiPageWikiLink Q626251.
- Q8565284 wikiPageWikiLink Q6545861.
- Q8565284 wikiPageWikiLink Q7214254.
- Q8565284 wikiPageWikiLink Q7300121.
- Q8565284 wikiPageWikiLink Q898797.
- Q8565284 wikiPageWikiLink Q903238.
- Q8565284 wikiPageWikiLink Q904407.
- Q8565284 wikiPageWikiLink Q916723.
- Q8565284 comment "Fragment-based lead discovery (FBLD) also known as fragment-based drug discovery (FBDD) is a method used for finding lead compounds as part of the drug discovery process. It is based on identifying small chemical fragments, which may bind only weakly to the biological target, and then growing them or combining them to produce a lead with a higher affinity. FBLD can be compared with high-throughput screening (HTS).".
- Q8565284 label "Fragment-based lead discovery".