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- Q850074 subject Q18924462.
- Q850074 subject Q7482068.
- Q850074 subject Q8919936.
- Q850074 abstract "Brotizolam (marketed under brand name Lendormin) is a sedative-hypnotic thienotriazolodiazepine drug which is a benzodiazepine analog. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to short-acting benzodiazepines such as triazolam. It is used in the short-term treatment of severe or debilitating insomnia. Brotizolam is an extremely potent drug and has shown anti-anxiety activity at doses as low as 0.08 to 0.1 milligrams, but the usual hypnotic dose of brotizolam is 0.125 to 0.25 milligrams, and it is rapidly eliminated with an average half-life of 4.4 hours (range 3.6–7.9 hours).The drug was developed by a team led by T Nishiyama while working for Takeda Chemical Industries in 1976 in Japan.Brotizolam is not approved for sale in the UK, United States or Canada. It is approved for sale in the Netherlands, Germany, Spain, Belgium, Luxembourg, Austria, Portugal, Israel, Italy, Taiwan and Japan.".
- Q850074 atcPrefix "N05".
- Q850074 atcSuffix "CD09".
- Q850074 bioavailability "48.0".
- Q850074 casNumber "57801-81-7".
- Q850074 drugbank "DB09017".
- Q850074 fdaUniiCode "5XZM1R3DKF".
- Q850074 iupacName "2-Bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine".
- Q850074 pubchem "2451".
- Q850074 thumbnail Brotizolam.svg?width=300.
- Q850074 wikiPageExternalLink pim919.htm.
- Q850074 wikiPageWikiLink Q1077823.
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- Q850074 wikiPageWikiLink Q8919936.
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- Q850074 atcPrefix "N05".
- Q850074 atcSuffix "CD09".
- Q850074 bioavailability "48".
- Q850074 casNumber "57801".
- Q850074 drugbank "DB09017".
- Q850074 iupacName "2".
- Q850074 pubchem "2451".
- Q850074 unii "5".
- Q850074 type ChemicalSubstance.
- Q850074 type Drug.
- Q850074 type ChemicalObject.
- Q850074 type Thing.
- Q850074 type Q8386.
- Q850074 comment "Brotizolam (marketed under brand name Lendormin) is a sedative-hypnotic thienotriazolodiazepine drug which is a benzodiazepine analog. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to short-acting benzodiazepines such as triazolam. It is used in the short-term treatment of severe or debilitating insomnia.".
- Q850074 label "Brotizolam".
- Q850074 seeAlso Q15043325.
- Q850074 depiction Brotizolam.svg.