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- Q808845 subject Q6814466.
- Q808845 subject Q7335370.
- Q808845 subject Q7931692.
- Q808845 subject Q8354154.
- Q808845 subject Q8852204.
- Q808845 abstract "Ceftazidime, sold under the brand names Fortaz and Tazicef, is an antibiotic useful for the treatment of a number of bacterial infections. It is a third-generation cephalosporin.As a class, cephalosporins have activity against Gram-positive and Gram-negative bacteria. The balance of activity tips toward Gram-positive organisms for earlier generations; later generations of cephalosporins have more Gram-negative coverage. Ceftazidime is one of the few in this class with activity against Pseudomonas. It is not active against methicillin-resistant Staphylococcus aureus.Third-generation cephalosporins differ from earlier generations in the presence of a C=N-OCH3 group in their chemical structure (Cefuroxime & Cefuzonam also bear this functional group but are only listed as class II). This group provides improved stability against certain beta-lactamase enzymes produced by Gram-negative bacteria. These bacterial enzymes rapidly destroy earlier-generation cephalosporins by breaking open the drug's beta-lactam chemical ring, leading to antibiotic resistance. Though initially active against these bacteria, with widespread use of third-generation cephalosporins, some Gram-negative bacteria known as extended-spectrum beta-lactamases (ESBLs) are even able to inactivate the third-generation cephalosporins. Infections caused by ESBL-producing Gram-negative bacteria are of particular concern in hospitals and other healthcare facilities.It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.".
- Q808845 atcPrefix "J01".
- Q808845 atcSuffix "DD02".
- Q808845 bioavailability "91.0".
- Q808845 casNumber "72558-82-8".
- Q808845 chEBI "3508".
- Q808845 drugbank "DB00438".
- Q808845 fdaUniiCode "DZR1ENT301".
- Q808845 iupacName "(6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetamido)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate".
- Q808845 pubchem "5481173".
- Q808845 thumbnail Ceftazidime.svg?width=300.
- Q808845 wikiPageWikiLink Q1053948.
- Q808845 wikiPageWikiLink Q1057079.
- Q808845 wikiPageWikiLink Q10876.
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- Q808845 wikiPageWikiLink Q20973563.
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- Q808845 wikiPageWikiLink Q271021.
- Q808845 wikiPageWikiLink Q311379.
- Q808845 wikiPageWikiLink Q37155.
- Q808845 wikiPageWikiLink Q408057.
- Q808845 wikiPageWikiLink Q413728.
- Q808845 wikiPageWikiLink Q417315.
- Q808845 wikiPageWikiLink Q418546.
- Q808845 wikiPageWikiLink Q432083.
- Q808845 wikiPageWikiLink Q4407.
- Q808845 wikiPageWikiLink Q5057303.
- Q808845 wikiPageWikiLink Q632006.
- Q808845 wikiPageWikiLink Q640448.
- Q808845 wikiPageWikiLink Q6814466.
- Q808845 wikiPageWikiLink Q7335370.
- Q808845 wikiPageWikiLink Q7931692.
- Q808845 wikiPageWikiLink Q8354154.
- Q808845 wikiPageWikiLink Q8852204.
- Q808845 wikiPageWikiLink Q899689.
- Q808845 wikiPageWikiLink Q9377.
- Q808845 wikiPageWikiLink Q963944.
- Q808845 atcPrefix "J01".
- Q808845 atcSuffix "DD02".
- Q808845 bioavailability "91.0".
- Q808845 casNumber "72558".
- Q808845 chebi "3508".
- Q808845 drugbank "DB00438".
- Q808845 iupacName "-7".
- Q808845 pubchem "5481173".
- Q808845 unii "DZR1ENT301".
- Q808845 type ChemicalSubstance.
- Q808845 type Drug.
- Q808845 type ChemicalObject.
- Q808845 type Thing.
- Q808845 type Q8386.
- Q808845 comment "Ceftazidime, sold under the brand names Fortaz and Tazicef, is an antibiotic useful for the treatment of a number of bacterial infections. It is a third-generation cephalosporin.As a class, cephalosporins have activity against Gram-positive and Gram-negative bacteria. The balance of activity tips toward Gram-positive organisms for earlier generations; later generations of cephalosporins have more Gram-negative coverage.".
- Q808845 label "Ceftazidime".
- Q808845 depiction Ceftazidime.svg.