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- Q7946880 subject Q7486806.
- Q7946880 subject Q8732563.
- Q7946880 subject Q8879081.
- Q7946880 subject Q8919936.
- Q7946880 abstract "WAY-161503 is a full agonist of 5-HT2C receptors (Ki = 3.3 nM for displacement of DOI), ~6-fold less potent at 5-HT2A receptors (Ki = 18 nM) and 20-fold less potent at 5-HT2B receptors (Ki = 60 nM). In functional studies, it stimulates calcium mobilization coupled to 5-HT2C, 5-HT2B, and 5-HT2A receptors with EC50 values of 0.8, 1.8, and 7 nM, respectively. WAY-161503 has been reported to produce dose-dependent decreases in food intake in 24-hour fasted normal Sprague-Dawley rats, diet-induced obese mice, and obese Zucker rats with ED50 values of 1.9, 6.8, and 0.73 mg/kg, respectively.WAY-161503 has been used to examine the role of 5-HT2C receptors in rodent models of depression, locomotion, reinforcement, or motivated behaviors.".
- Q7946880 casNumber "75704-24-4".
- Q7946880 iupacName "8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one".
- Q7946880 pubchem "3906894".
- Q7946880 thumbnail WAY-161503.svg?width=300.
- Q7946880 wikiPageWikiLink Q14891424.
- Q7946880 wikiPageWikiLink Q18027434.
- Q7946880 wikiPageWikiLink Q18027437.
- Q7946880 wikiPageWikiLink Q209251.
- Q7946880 wikiPageWikiLink Q7486806.
- Q7946880 wikiPageWikiLink Q8732563.
- Q7946880 wikiPageWikiLink Q8879081.
- Q7946880 wikiPageWikiLink Q8919936.
- Q7946880 casNumber "75704".
- Q7946880 iupacName "89".
- Q7946880 pubchem "3906894".
- Q7946880 type ChemicalSubstance.
- Q7946880 type Drug.
- Q7946880 type ChemicalObject.
- Q7946880 type Thing.
- Q7946880 type Q8386.
- Q7946880 comment "WAY-161503 is a full agonist of 5-HT2C receptors (Ki = 3.3 nM for displacement of DOI), ~6-fold less potent at 5-HT2A receptors (Ki = 18 nM) and 20-fold less potent at 5-HT2B receptors (Ki = 60 nM). In functional studies, it stimulates calcium mobilization coupled to 5-HT2C, 5-HT2B, and 5-HT2A receptors with EC50 values of 0.8, 1.8, and 7 nM, respectively.".
- Q7946880 label "WAY-161503".
- Q7946880 depiction WAY-161503.svg.