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- Q7881588 subject Q7211328.
- Q7881588 subject Q8593033.
- Q7881588 abstract "Umirolimus (INN/USAN), is a macrocyclic lactone, a highly lipophilic derivative of sirolimus, an immunosuppressant. This drug is proprietary to Biosensors International, which uses it in its own drug-eluting stents, and licenses it to partners such as Terumo. Umirolimus inhibits T cell and smooth muscle cell proliferation, and was designed for use in drug eluting stents. This analog has a chemical modification at position 40 of the rapamycin ring. It has potent immunosuppressive properties that are similar to those of sirolimus, but the drug is more rapidly absorbed by the vessel wall, readily attaches and enters smooth muscle cell membranes causing cell cycle arrest at G0, and is comparable to sirolimus in terms of potency.".
- Q7881588 casNumber "851536-75-9".
- Q7881588 thumbnail Biolimus_A9.png?width=300.
- Q7881588 wikiPageWikiLink Q1455316.
- Q7881588 wikiPageWikiLink Q193529.
- Q7881588 wikiPageWikiLink Q208453.
- Q7881588 wikiPageWikiLink Q32089.
- Q7881588 wikiPageWikiLink Q3518961.
- Q7881588 wikiPageWikiLink Q3973120.
- Q7881588 wikiPageWikiLink Q4915279.
- Q7881588 wikiPageWikiLink Q4926095.
- Q7881588 wikiPageWikiLink Q7211328.
- Q7881588 wikiPageWikiLink Q824258.
- Q7881588 wikiPageWikiLink Q8593033.
- Q7881588 casNumber "851536".
- Q7881588 type ChemicalSubstance.
- Q7881588 type Drug.
- Q7881588 type ChemicalObject.
- Q7881588 type Thing.
- Q7881588 type Q8386.
- Q7881588 comment "Umirolimus (INN/USAN), is a macrocyclic lactone, a highly lipophilic derivative of sirolimus, an immunosuppressant. This drug is proprietary to Biosensors International, which uses it in its own drug-eluting stents, and licenses it to partners such as Terumo. Umirolimus inhibits T cell and smooth muscle cell proliferation, and was designed for use in drug eluting stents. This analog has a chemical modification at position 40 of the rapamycin ring.".
- Q7881588 label "Umirolimus".
- Q7881588 depiction Biolimus_A9.png.