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- Q7860880 subject Q8395861.
- Q7860880 abstract "In molecular biology Type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA, relax the strand, and reanneal the strand. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB. Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. Type IB topoisomerases change the linking number by multiples of 1 (n). Historically, type IA topoisomerases are referred to as prokaryotic topo I, while type IB topoisomerases are referred to as eukaryotic topoisomerase. This distinction, however, no longer applies as type IA and type IB topoisomerases exist in all domains of life.Functionally, these subclasses perform very specialized functions. Prokaryotic topoisomerase I (topo IA) can only relax negative supercoiled DNA, whereas eukaryotic topoisomerase I (topo IB) can introduce positive supercoils, separating the DNA of daughter chromosomes after DNA replication, and relax DNA.".
- Q7860880 symbol "VirDNA-topo-I_N".
- Q7860880 thumbnail PDB_1vcc_EBI.jpg?width=300.
- Q7860880 wikiPageExternalLink 5.99.1.2.
- Q7860880 wikiPageExternalLink 5.99.1.3.
- Q7860880 wikiPageExternalLink explore.do?structureId=2csb.
- Q7860880 wikiPageExternalLink explore.do?structureId=2csd.
- Q7860880 wikiPageWikiLink Q103537.
- Q7860880 wikiPageWikiLink Q130996.
- Q7860880 wikiPageWikiLink Q133226.
- Q7860880 wikiPageWikiLink Q15712714.
- Q7860880 wikiPageWikiLink Q177900.
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- Q7860880 wikiPageWikiLink Q19088.
- Q7860880 wikiPageWikiLink Q2000614.
- Q7860880 wikiPageWikiLink Q211675.
- Q7860880 wikiPageWikiLink Q2700637.
- Q7860880 wikiPageWikiLink Q2914865.
- Q7860880 wikiPageWikiLink Q3618655.
- Q7860880 wikiPageWikiLink Q37748.
- Q7860880 wikiPageWikiLink Q3787274.
- Q7860880 wikiPageWikiLink Q407828.
- Q7860880 wikiPageWikiLink Q411991.
- Q7860880 wikiPageWikiLink Q412197.
- Q7860880 wikiPageWikiLink Q412639.
- Q7860880 wikiPageWikiLink Q419953.
- Q7860880 wikiPageWikiLink Q419964.
- Q7860880 wikiPageWikiLink Q423026.
- Q7860880 wikiPageWikiLink Q42989.
- Q7860880 wikiPageWikiLink Q483261.
- Q7860880 wikiPageWikiLink Q7430.
- Q7860880 wikiPageWikiLink Q785022.
- Q7860880 wikiPageWikiLink Q8047.
- Q7860880 wikiPageWikiLink Q80863.
- Q7860880 wikiPageWikiLink Q8395861.
- Q7860880 wikiPageWikiLink Q863983.
- Q7860880 wikiPageWikiLink Q958797.
- Q7860880 symbol "VirDNA-topo-I_N".
- Q7860880 type Biomolecule.
- Q7860880 type Protein.
- Q7860880 type Thing.
- Q7860880 type Q206229.
- Q7860880 type Q8054.
- Q7860880 comment "In molecular biology Type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA, relax the strand, and reanneal the strand. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB. Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. Type IB topoisomerases change the linking number by multiples of 1 (n).".
- Q7860880 label "Type I topoisomerase".
- Q7860880 depiction PDB_1vcc_EBI.jpg.