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- Q7784674 subject Q7145140.
- Q7784674 subject Q7486806.
- Q7784674 subject Q8220082.
- Q7784674 subject Q9052268.
- Q7784674 abstract "Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability. Studies have shown that thiolutin inhibits adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin and thus suppresses tumor cell-induced angiogenesis in vivo.Thiolutin is formed in submerged fermentation by several strains of Streptomycetes luteosporeus. Some sources erroneously specify "aureothricin" as a synonym of thiolutin. Aureothricin is an antibiotic very similar to thiolutin, and is created as a by-product during the thiolutin fermentation.".
- Q7784674 atcPrefix "none".
- Q7784674 casNumber "87-11-6".
- Q7784674 iupacName "N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide".
- Q7784674 pubchem "6870".
- Q7784674 thumbnail Thiolutin.png?width=300.
- Q7784674 wikiPageWikiLink Q1144013.
- Q7784674 wikiPageWikiLink Q14916393.
- Q7784674 wikiPageWikiLink Q3109391.
- Q7784674 wikiPageWikiLink Q416796.
- Q7784674 wikiPageWikiLink Q5939177.
- Q7784674 wikiPageWikiLink Q7145140.
- Q7784674 wikiPageWikiLink Q719725.
- Q7784674 wikiPageWikiLink Q7486806.
- Q7784674 wikiPageWikiLink Q8220082.
- Q7784674 wikiPageWikiLink Q845523.
- Q7784674 wikiPageWikiLink Q9052268.
- Q7784674 atcPrefix "none".
- Q7784674 casNumber "87".
- Q7784674 iupacName "N-acetamide".
- Q7784674 pubchem "6870".
- Q7784674 type ChemicalSubstance.
- Q7784674 type Drug.
- Q7784674 type ChemicalObject.
- Q7784674 type Thing.
- Q7784674 type Q8386.
- Q7784674 comment "Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability.".
- Q7784674 label "Thiolutin".
- Q7784674 depiction Thiolutin.png.