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- Q774909 subject Q6357395.
- Q774909 abstract "Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. This is achieved by increasing expression of the glycoprotein complex GPIIb/IIIa on the cell membrane of platelets. The same effect is also achieved by ADP in platelet stimulation, which is blocked by clopidogrel. Circulating fibrinogen binds these receptors on adjacent platelets, further strengthening the clot. Thromboxane A2 is also a known vasoconstrictor and is especially important during tissue injury and inflammation. It is also regarded as responsible for Prinzmetal's angina.Receptors that mediate TXA2 actions are thromboxane A2 receptors. The human TXA2 receptor (TP) is a typical G protein-coupled receptor (GPCR) with seven transmembrane segments. In humans, two TP receptor splice variants - TPα and TPβ - have so far been cloned.".
- Q774909 thumbnail Thromboxane_A2_acsv.svg?width=300.
- Q774909 wikiPageWikiLink Q1067506.
- Q774909 wikiPageWikiLink Q1469637.
- Q774909 wikiPageWikiLink Q14881694.
- Q774909 wikiPageWikiLink Q14905573.
- Q774909 wikiPageWikiLink Q18216.
- Q774909 wikiPageWikiLink Q185253.
- Q774909 wikiPageWikiLink Q21099593.
- Q774909 wikiPageWikiLink Q2335787.
- Q774909 wikiPageWikiLink Q2806929.
- Q774909 wikiPageWikiLink Q3009646.
- Q774909 wikiPageWikiLink Q381899.
- Q774909 wikiPageWikiLink Q410237.
- Q774909 wikiPageWikiLink Q410251.
- Q774909 wikiPageWikiLink Q412212.
- Q774909 wikiPageWikiLink Q416567.
- Q774909 wikiPageWikiLink Q4864593.
- Q774909 wikiPageWikiLink Q6357395.
- Q774909 type ChemicalCompound.
- Q774909 type ChemicalSubstance.
- Q774909 type ChemicalObject.
- Q774909 type Thing.
- Q774909 type Q11173.
- Q774909 comment "Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. This is achieved by increasing expression of the glycoprotein complex GPIIb/IIIa on the cell membrane of platelets. The same effect is also achieved by ADP in platelet stimulation, which is blocked by clopidogrel.".
- Q774909 label "Thromboxane A2".
- Q774909 depiction Thromboxane_A2_acsv.svg.