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- Q7685917 subject Q16807304.
- Q7685917 subject Q7064899.
- Q7685917 subject Q8606718.
- Q7685917 abstract "Targeted therapy of lung cancer refers to using agents specifically designed to selectively target molecular pathways responsible for, or that substantially drive, the malignant phenotype of lung cancer cells, and as a consequence of this (relative) selectivity, cause fewer toxic effects on normal cells.Most previous chemotherapy drugs for cancer were (relatively) nonselective in their activity. Although their exact mechanisms of action were varied and complex, they generally worked by damaging cells undergoing mitosis, which is usually more common in malignant tumors than in most normal tissues. Targeted agents are designed to be selective in their effects by modulating the activity of proteins necessary and essential for oncogenesis and maintenance of cancer, particularly enzymes driving the uncontrolled growth, angiogenesis, invasiveness, and metastasis characteristic of malignant tumors. The increased differential activity usually results in fewer troubling side effects for cancer patients, particularly less nausea, vomiting, and death of cells in the bone marrow and gastrointestinal tract, and increased effectiveness against tumor cells.".
- Q7685917 wikiPageExternalLink lung.
- Q7685917 wikiPageExternalLink BB10.pdf.
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- Q7685917 type Thing.
- Q7685917 comment "Targeted therapy of lung cancer refers to using agents specifically designed to selectively target molecular pathways responsible for, or that substantially drive, the malignant phenotype of lung cancer cells, and as a consequence of this (relative) selectivity, cause fewer toxic effects on normal cells.Most previous chemotherapy drugs for cancer were (relatively) nonselective in their activity.".
- Q7685917 label "Targeted therapy of lung cancer".
- Q7685917 seeAlso Q5150915.
- Q7685917 seeAlso Q6152005.