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- Q7662829 subject Q8802898.
- Q7662829 abstract "The syntrophins are a family of five 60-kiloDalton proteins that are associated with dystrophin, the protein associated with Duchenne muscular dystrophy and Becker muscular dystrophy. The name comes from the Greek word syntrophos, meaning "companion." The five syntrophins are encoded by separate genes and are termed α, β1, β2, γ1, and γ2. Syntrophin was first identified as a dystrophin-associated protein present in the Torpedo electric organ (originally called "58K protein"). Subsequently, α-syntrophin was shown to be the predominant isoform in skeletal muscle where it is localized on the sarcolemma and enriched at the neuromuscular junction. The β-syntrophins and γ2-syntrophin are also present in skeletal muscle but also are in most other tissues. The expression of γ1-syntrophin is mostly confined to brain. The syntrophins are adapter proteins that use their multiple protein interaction domains (two pleckstrin homology domains and a PDZ domain) to localize a variety of signaling proteins (kinases, ion channels, water channels, nitric oxide synthase) to specific intracellular locations. α-Syntrophin binds to nNOS in the dystrophin-associated glycoprotein complex in skeletal muscle cells. There it produces NO upon muscle contraction leading to dilation of the arteries in the local area.".
- Q7662829 wikiPageWikiLink Q1048687.
- Q7662829 wikiPageWikiLink Q1136436.
- Q7662829 wikiPageWikiLink Q1327533.
- Q7662829 wikiPageWikiLink Q14864292.
- Q7662829 wikiPageWikiLink Q1545001.
- Q7662829 wikiPageWikiLink Q1648484.
- Q7662829 wikiPageWikiLink Q18030177.
- Q7662829 wikiPageWikiLink Q18031636.
- Q7662829 wikiPageWikiLink Q18031637.
- Q7662829 wikiPageWikiLink Q18031640.
- Q7662829 wikiPageWikiLink Q18040975.
- Q7662829 wikiPageWikiLink Q206675.
- Q7662829 wikiPageWikiLink Q210973.
- Q7662829 wikiPageWikiLink Q2484592.
- Q7662829 wikiPageWikiLink Q36506.
- Q7662829 wikiPageWikiLink Q417619.
- Q7662829 wikiPageWikiLink Q421851.
- Q7662829 wikiPageWikiLink Q483261.
- Q7662829 wikiPageWikiLink Q5964993.
- Q7662829 wikiPageWikiLink Q609809.
- Q7662829 wikiPageWikiLink Q62536.
- Q7662829 wikiPageWikiLink Q7187.
- Q7662829 wikiPageWikiLink Q7391911.
- Q7662829 wikiPageWikiLink Q776995.
- Q7662829 wikiPageWikiLink Q7973466.
- Q7662829 wikiPageWikiLink Q8054.
- Q7662829 wikiPageWikiLink Q8802898.
- Q7662829 wikiPageWikiLink Q898273.
- Q7662829 wikiPageWikiLink Q901100.
- Q7662829 comment "The syntrophins are a family of five 60-kiloDalton proteins that are associated with dystrophin, the protein associated with Duchenne muscular dystrophy and Becker muscular dystrophy. The name comes from the Greek word syntrophos, meaning "companion." The five syntrophins are encoded by separate genes and are termed α, β1, β2, γ1, and γ2. Syntrophin was first identified as a dystrophin-associated protein present in the Torpedo electric organ (originally called "58K protein").".
- Q7662829 label "Syntrophin".