Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q7339205> ?p ?o }
Showing triples 1 to 41 of
41
with 100 triples per page.
- Q7339205 subject Q6946436.
- Q7339205 subject Q7403741.
- Q7339205 subject Q7486806.
- Q7339205 subject Q8825317.
- Q7339205 subject Q8919936.
- Q7339205 abstract "Ro5-4864 (4'-chlorodiazepam) is a drug which is a benzodiazepine derivative of diazepam. However unlike most benzodiazepine derivatives, Ro5-4864 lacks affinity for GABAA receptors and lacks typical benzodiazepine effects, instead being sedative yet also convulsant and anxiogenic in effects. Ro5-4864 was found to be a potent ligand for the "peripheral benzodiazepine receptor", later renamed to mitochondrial translocator protein 18kDa (TSPO). Despite its convulsant effects, at lower doses Ro5-4864 has proved to be neuroprotective and has become widely used for research into the role of the TSPO protein in neurotoxicity. In vitro studies and rodent models also suggest the possibility of analgesic, antidepressant, cardioprotective, and anti-cancer effects.".
- Q7339205 casNumber "14439-61-3".
- Q7339205 iupacName "7-Chloro-5-(4-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one".
- Q7339205 pubchem "1688".
- Q7339205 thumbnail Ro5-4864.svg?width=300.
- Q7339205 wikiPageWikiLink Q14913474.
- Q7339205 wikiPageWikiLink Q15408412.
- Q7339205 wikiPageWikiLink Q173235.
- Q7339205 wikiPageWikiLink Q1981368.
- Q7339205 wikiPageWikiLink Q208467.
- Q7339205 wikiPageWikiLink Q210402.
- Q7339205 wikiPageWikiLink Q213907.
- Q7339205 wikiPageWikiLink Q221681.
- Q7339205 wikiPageWikiLink Q4778117.
- Q7339205 wikiPageWikiLink Q5166679.
- Q7339205 wikiPageWikiLink Q60147.
- Q7339205 wikiPageWikiLink Q6946436.
- Q7339205 wikiPageWikiLink Q7119490.
- Q7339205 wikiPageWikiLink Q7403741.
- Q7339205 wikiPageWikiLink Q7486806.
- Q7339205 wikiPageWikiLink Q76560.
- Q7339205 wikiPageWikiLink Q83871.
- Q7339205 wikiPageWikiLink Q847705.
- Q7339205 wikiPageWikiLink Q8825317.
- Q7339205 wikiPageWikiLink Q8919936.
- Q7339205 casNumber "14439".
- Q7339205 iupacName "7".
- Q7339205 pubchem "1688".
- Q7339205 type ChemicalSubstance.
- Q7339205 type Drug.
- Q7339205 type ChemicalObject.
- Q7339205 type Thing.
- Q7339205 type Q8386.
- Q7339205 comment "Ro5-4864 (4'-chlorodiazepam) is a drug which is a benzodiazepine derivative of diazepam. However unlike most benzodiazepine derivatives, Ro5-4864 lacks affinity for GABAA receptors and lacks typical benzodiazepine effects, instead being sedative yet also convulsant and anxiogenic in effects. Ro5-4864 was found to be a potent ligand for the "peripheral benzodiazepine receptor", later renamed to mitochondrial translocator protein 18kDa (TSPO).".
- Q7339205 label "Ro5-4864".
- Q7339205 depiction Ro5-4864.svg.