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- Q7316768 subject Q7221143.
- Q7316768 subject Q8527128.
- Q7316768 abstract "Retinal precursor cells are biological cells that differentiate into the various cell types of the retina during development. In the vertebrate, these retinal cells differentiate into seven cell types, including retinal ganglion cells, amacrine cells, bipolar cells, horizontal cells, rod photoreceptors, cone photoreceptors, and Müller glia cells. During embryogenesis, retinal cells originate from the anterior portion of the neural plate termed the eye field. Eye field cells with a retinal fate express several transcription factor markers including Rx1, Pax6, and Lhx2. The eye field gives rise to the optic vesicle and then to the optic cup. The retina is generated from the precursor cells within the inner layer of the optic cup, as opposed to the retinal pigment epithelium that originate from the outer layer of the optic cup. In general, the developing retina is organized so that the least-committed precursor cells are located in the periphery of the retina, while the committed cells are located in the center of the retina. The differentiation of retinal precursor cells into the mature cell types found in the retina is coordinated in time and space by factors within the cell as well as factors in the environment of the cell. One example of an intrinsic regulator of this process is the transcription factor Ath5. Ath5 expression in retinal progenitor cells biases their differentiation into a retinal ganglion cell fate. An example of an environmental factor is the morphogen sonic hedge hog (Shh). Shh has been shown to repress the differentiation of precursor cells into retinal ganglion cells.".
- Q7316768 thumbnail Human_eye_cross-sectional_view_grayscale.png?width=300.
- Q7316768 wikiPageWikiLink Q147298.
- Q7316768 wikiPageWikiLink Q14860072.
- Q7316768 wikiPageWikiLink Q14916213.
- Q7316768 wikiPageWikiLink Q155769.
- Q7316768 wikiPageWikiLink Q1628177.
- Q7316768 wikiPageWikiLink Q169342.
- Q7316768 wikiPageWikiLink Q2346242.
- Q7316768 wikiPageWikiLink Q452595.
- Q7316768 wikiPageWikiLink Q505544.
- Q7316768 wikiPageWikiLink Q5505090.
- Q7316768 wikiPageWikiLink Q690588.
- Q7316768 wikiPageWikiLink Q7098790.
- Q7316768 wikiPageWikiLink Q7221143.
- Q7316768 wikiPageWikiLink Q735343.
- Q7316768 wikiPageWikiLink Q760262.
- Q7316768 wikiPageWikiLink Q8527128.
- Q7316768 wikiPageWikiLink Q927337.
- Q7316768 comment "Retinal precursor cells are biological cells that differentiate into the various cell types of the retina during development. In the vertebrate, these retinal cells differentiate into seven cell types, including retinal ganglion cells, amacrine cells, bipolar cells, horizontal cells, rod photoreceptors, cone photoreceptors, and Müller glia cells. During embryogenesis, retinal cells originate from the anterior portion of the neural plate termed the eye field.".
- Q7316768 label "Retinal precursor cells".
- Q7316768 depiction Human_eye_cross-sectional_view_grayscale.png.
