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- Q7313254 subject Q10195735.
- Q7313254 abstract "The Renin stability regulatory element (REN-SRE) is a cis-acting element identified in the 3'untranslated region (3'UTR) of the renin (REN) gene. It acts to regulate the levels of renin protein produced in the cell. Renin is secreted by renal juxtaglomerular cells and catalyses the conversion of angiotensinogen into angiotensin I which is the rate-limiting step in the production of angiotensin II. Angiotensin II induces hypertension and REN therefore requires tight expression control.REN-SRE is thought to act by destabilising the REN messenger RNA (mRNA) and promoting degradation of the mRNA sequence. It has been found that a number of proteins bind to the REN-SRE to stabilise the mRNA and promote translation.".
- Q7313254 thumbnail RF00180.jpg?width=300.
- Q7313254 wikiPageWikiLink Q10195735.
- Q7313254 wikiPageWikiLink Q1093165.
- Q7313254 wikiPageWikiLink Q14859578.
- Q7313254 wikiPageWikiLink Q14859647.
- Q7313254 wikiPageWikiLink Q15712714.
- Q7313254 wikiPageWikiLink Q185917.
- Q7313254 wikiPageWikiLink Q188928.
- Q7313254 wikiPageWikiLink Q19088.
- Q7313254 wikiPageWikiLink Q2596226.
- Q7313254 wikiPageWikiLink Q3272830.
- Q7313254 wikiPageWikiLink Q41861.
- Q7313254 wikiPageWikiLink Q4995178.
- Q7313254 wikiPageWikiLink Q82264.
- Q7313254 comment "The Renin stability regulatory element (REN-SRE) is a cis-acting element identified in the 3'untranslated region (3'UTR) of the renin (REN) gene. It acts to regulate the levels of renin protein produced in the cell. Renin is secreted by renal juxtaglomerular cells and catalyses the conversion of angiotensinogen into angiotensin I which is the rate-limiting step in the production of angiotensin II.".
- Q7313254 label "Renin stability regulatory element (REN-SRE)".
- Q7313254 depiction RF00180.jpg.