Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q7278498> ?p ?o }
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- Q7278498 subject Q7348588.
- Q7278498 subject Q8802898.
- Q7278498 subject Q9089708.
- Q7278498 abstract "Rabaptin is a key protein involved in regeneration of injured axons.Regeneration of injured axons at neuromuscular junctions is regulated by extra-cellular protein factors that promote neurite outgrowth. A novel neurite outgrowth factor from chick denervated skeletal muscle has been cloned and characterised. The protein, termed neurocrescin (rabaptin), has been shown to be secreted in an activity-dependent fashion.Rabaptin is a 100kDa coiled-coil protein that interacts with the GTP form of the small GTPase Rab5 (see RAB5A, RAB5B, RAB5C) a potent regulator of endocytic transport. It is mainly cytosolic, but a fraction co-localises with Rab5 to early endosomes. Rab5 recruits rabaptin-5 to purified early endosomes in a GTP-dependent manner, demonstrating functional similarities with other members of the Ras family. Immunodepletion of rabaptin-5 from cytosol strongly inhibits Rab5-dependent early endosome membrane fusion. Thus, rabaptin-5 is a Rab effector required for membrane docking and fusion. Rab5 contributes to early endosome fusion that works through the coordination of other effector proteins, as mentioned above. Rabaptin components may serve to control the SNARE activity which are vital in membrane fusion.".
- Q7278498 symbol "Rabaptin".
- Q7278498 thumbnail 1TU3.pdb.png?width=300.
- Q7278498 wikiPageWikiLink Q1048687.
- Q7278498 wikiPageWikiLink Q1187030.
- Q7278498 wikiPageWikiLink Q1534415.
- Q7278498 wikiPageWikiLink Q178999.
- Q7278498 wikiPageWikiLink Q18030993.
- Q7278498 wikiPageWikiLink Q18030994.
- Q7278498 wikiPageWikiLink Q18031004.
- Q7278498 wikiPageWikiLink Q18033859.
- Q7278498 wikiPageWikiLink Q193119.
- Q7278498 wikiPageWikiLink Q284398.
- Q7278498 wikiPageWikiLink Q310425.
- Q7278498 wikiPageWikiLink Q415071.
- Q7278498 wikiPageWikiLink Q6556360.
- Q7278498 wikiPageWikiLink Q7348588.
- Q7278498 wikiPageWikiLink Q769143.
- Q7278498 wikiPageWikiLink Q776995.
- Q7278498 wikiPageWikiLink Q824237.
- Q7278498 wikiPageWikiLink Q826582.
- Q7278498 wikiPageWikiLink Q8802898.
- Q7278498 wikiPageWikiLink Q903650.
- Q7278498 wikiPageWikiLink Q9089708.
- Q7278498 symbol "Rabaptin".
- Q7278498 type Biomolecule.
- Q7278498 type Protein.
- Q7278498 type Thing.
- Q7278498 type Q206229.
- Q7278498 type Q8054.
- Q7278498 comment "Rabaptin is a key protein involved in regeneration of injured axons.Regeneration of injured axons at neuromuscular junctions is regulated by extra-cellular protein factors that promote neurite outgrowth. A novel neurite outgrowth factor from chick denervated skeletal muscle has been cloned and characterised.".
- Q7278498 label "Rabaptin".
- Q7278498 depiction 1TU3.pdb.png.