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- Q7252856 subject Q6853449.
- Q7252856 abstract "Proximal renal tubular acidosis (pRTA) or Type 2 Renal tubular acidosis (RTA) is a type of RTA caused by a failure of the proximal tubular cells to reabsorb filtered bicarbonate from the urine, leading to urinary bicarbonate wasting and subsequent acidemia. The distal intercalated cells function normally, so the acidemia is less severe than dRTA and the urine can acidify to a pH of less than 5.3. pRTA also has several causes, and may occasionally be present as a solitary defect, but is usually associated with a more generalised dysfunction of the proximal tubular cells called Fanconi syndrome where there is also phosphaturia, glycosuria, aminoaciduria, uricosuria and tubular proteinuria.The principal feature of Fanconi syndrome is bone demineralization (osteomalacia or rickets) due to phosphate wasting.".
- Q7252856 meshId "D000141".
- Q7252856 omim "179830".
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- Q7252856 wikiPageWikiLink Q6853449.
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- Q7252856 meshid "D000141".
- Q7252856 name "Proximal renal tubular acidosis".
- Q7252856 omim "179830".
- Q7252856 type Disease.
- Q7252856 type Thing.
- Q7252856 type Q12136.
- Q7252856 comment "Proximal renal tubular acidosis (pRTA) or Type 2 Renal tubular acidosis (RTA) is a type of RTA caused by a failure of the proximal tubular cells to reabsorb filtered bicarbonate from the urine, leading to urinary bicarbonate wasting and subsequent acidemia. The distal intercalated cells function normally, so the acidemia is less severe than dRTA and the urine can acidify to a pH of less than 5.3.".
- Q7252856 label "Proximal renal tubular acidosis".
- Q7252856 name "Proximal renal tubular acidosis".