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- Q7226556 subject Q7217197.
- Q7226556 abstract "PCR inhibitors are any factor which prevent the amplification of nucleic acids through the polymerase chain reaction (PCR). PCR inhibition is the most common cause of amplification failure when sufficient copies of DNA are present. PCR inhibitors usually affect PCR through interaction with DNA or interference with the DNA polymerase. Inhibitors can escape removal during the DNA purification procedure by binding directly to single or double-stranded DNA. Alternatively, by reducing the availability of cofactors (such as Mg2+) or otherwise interfering with their interaction with the DNA polymerase, PCR is inhibited.In a multiplex PCR reaction, it is possible for the different sequences to suffer from different inhibition effects to different extents, leading to disparity in their relative amplifications.".
- Q7226556 wikiPageExternalLink index.php?title=PCR_inhibitors.
- Q7226556 wikiPageWikiLink Q123619.
- Q7226556 wikiPageWikiLink Q176996.
- Q7226556 wikiPageWikiLink Q1952456.
- Q7226556 wikiPageWikiLink Q206286.
- Q7226556 wikiPageWikiLink Q2620381.
- Q7226556 wikiPageWikiLink Q309660.
- Q7226556 wikiPageWikiLink Q407280.
- Q7226556 wikiPageWikiLink Q422241.
- Q7226556 wikiPageWikiLink Q7217197.
- Q7226556 wikiPageWikiLink Q7226557.
- Q7226556 comment "PCR inhibitors are any factor which prevent the amplification of nucleic acids through the polymerase chain reaction (PCR). PCR inhibition is the most common cause of amplification failure when sufficient copies of DNA are present. PCR inhibitors usually affect PCR through interaction with DNA or interference with the DNA polymerase. Inhibitors can escape removal during the DNA purification procedure by binding directly to single or double-stranded DNA.".
- Q7226556 label "Polymerase chain reaction inhibitors".