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- Q7135605 subject Q6368047.
- Q7135605 abstract "Paraoxonases are a group, or family, of enzymes consisting of three sub-types that were originally discovered for their involvement in the hydrolysis of organophosphates. Further research has indicated the enzymatic activity of paraoxonases is more diversified than its activity as an organophosphatase. Esterase and Lactonase/Lactonizing activity has also been observed from these enzymes and though the physiologically relevant substrates for these enzymes are unknown, it is likely that lactones are the main substrate (although there is a relatively high level of variation in substrate specificity among these enzymes). Most of the studies on the paraoxonase family have specifically looked at the paraoxonae 1 type, leaving much to be learned about the remaining two. The study of this enzyme family has many potential consequences in preventative medicine and toxicology as well as in certain societal contexts. The genes that encode for these enzymes have a number of different polymorphisms, which created additional interest in the study of this enzyme group and its potential cultural variations. Additional research on the inhibition and selective inhibition, specifically of PON1, has been done to shed some light on the connections between decreases in enzymatic activity of individuals with cardiovascular diseases. Evidence also suggests that this family of enzymes has some role in our innate immune system.".
- Q7135605 arm "q".
- Q7135605 band "21.3".
- Q7135605 chromosome "7".
- Q7135605 ecNumber "3.1.8.1".
- Q7135605 entrezgene "5444".
- Q7135605 entrezgene "5445".
- Q7135605 entrezgene "5446".
- Q7135605 hgncid "9204".
- Q7135605 hgncid "9205".
- Q7135605 hgncid "9206".
- Q7135605 omim "168820".
- Q7135605 omim "602447".
- Q7135605 omim "602720".
- Q7135605 refseq "NM_000305".
- Q7135605 refseq "NM_000446".
- Q7135605 refseq "NM_000940".
- Q7135605 symbol "PON".
- Q7135605 symbol "PON1".
- Q7135605 symbol "PON2".
- Q7135605 symbol "PON3".
- Q7135605 thumbnail Serum_Paraoxonase-1_PyMol_video.gif?width=300.
- Q7135605 uniprot "P27169".
- Q7135605 uniprot "Q15165".
- Q7135605 uniprot "Q15166".
- Q7135605 wikiPageWikiLink Q103135.
- Q7135605 wikiPageWikiLink Q1058276.
- Q7135605 wikiPageWikiLink Q12119506.
- Q7135605 wikiPageWikiLink Q12252367.
- Q7135605 wikiPageWikiLink Q133948.
- Q7135605 wikiPageWikiLink Q18030661.
- Q7135605 wikiPageWikiLink Q18030662.
- Q7135605 wikiPageWikiLink Q18030663.
- Q7135605 wikiPageWikiLink Q181136.
- Q7135605 wikiPageWikiLink Q185906.
- Q7135605 wikiPageWikiLink Q2765105.
- Q7135605 wikiPageWikiLink Q28749.
- Q7135605 wikiPageWikiLink Q36496.
- Q7135605 wikiPageWikiLink Q410020.
- Q7135605 wikiPageWikiLink Q411097.
- Q7135605 wikiPageWikiLink Q412556.
- Q7135605 wikiPageWikiLink Q416108.
- Q7135605 wikiPageWikiLink Q418750.
- Q7135605 wikiPageWikiLink Q4802704.
- Q7135605 wikiPageWikiLink Q485277.
- Q7135605 wikiPageWikiLink Q485680.
- Q7135605 wikiPageWikiLink Q5532877.
- Q7135605 wikiPageWikiLink Q59078.
- Q7135605 wikiPageWikiLink Q6030084.
- Q7135605 wikiPageWikiLink Q609809.
- Q7135605 wikiPageWikiLink Q6368047.
- Q7135605 wikiPageWikiLink Q6469031.
- Q7135605 wikiPageWikiLink Q657319.
- Q7135605 wikiPageWikiLink Q844935.
- Q7135605 wikiPageWikiLink Q867060.
- Q7135605 wikiPageWikiLink Q898539.
- Q7135605 wikiPageWikiLink Q898814.
- Q7135605 altsymbols "PON".
- Q7135605 arm "q".
- Q7135605 band "21.3".
- Q7135605 chromosome "7".
- Q7135605 ecnumber "3.1".
- Q7135605 entrezgene "5444".
- Q7135605 entrezgene "5445".
- Q7135605 entrezgene "5446".
- Q7135605 hgncid "9204".
- Q7135605 hgncid "9205".
- Q7135605 hgncid "9206".
- Q7135605 name Q18030661.
- Q7135605 name Q18030662.
- Q7135605 name Q18030663.
- Q7135605 omim "168820".
- Q7135605 omim "602447".
- Q7135605 omim "602720".
- Q7135605 refseq "NM_000305".
- Q7135605 refseq "NM_000446".
- Q7135605 refseq "NM_000940".
- Q7135605 symbol Q18030661.
- Q7135605 symbol Q18030662.
- Q7135605 symbol Q18030663.
- Q7135605 uniprot "P27169".
- Q7135605 uniprot "Q15165".
- Q7135605 uniprot "Q15166".
- Q7135605 type Biomolecule.
- Q7135605 type Protein.
- Q7135605 type Thing.
- Q7135605 type Q206229.
- Q7135605 type Q8054.
- Q7135605 comment "Paraoxonases are a group, or family, of enzymes consisting of three sub-types that were originally discovered for their involvement in the hydrolysis of organophosphates. Further research has indicated the enzymatic activity of paraoxonases is more diversified than its activity as an organophosphatase.".
- Q7135605 label "Paraoxonase".
- Q7135605 depiction Serum_Paraoxonase-1_PyMol_video.gif.
- Q7135605 name "paraoxonase 1".
- Q7135605 name "paraoxonase 2".
- Q7135605 name "paraoxonase 3".