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- Q7107235 subject Q7063594.
- Q7107235 abstract "Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis. Once inside the cytoplasm, pinocytic vacuoles combine with each other and with lysosomes to form large vacuoles that appear transparent under microscopic examination.There may be no symptomatic presentation with this condition, or it may confused with other nephrotic conditions such as Tubular calcineurin-inhibitor toxicity. Affected cells of the proximal tubule may be passed in the urine, but a kidney biopsy is the only sure way to make a diagnosis.Responsible exogenous solutes include sucrose-containing IVIg, mannitol, dextran, contrast dye, and hydroxyethyl starch. Prevention includes standard preventions for iatrogenic kidney damage. Osmotic nephrosis is usually reversible but can lead to chronic renal failure.".
- Q7107235 wikiPageExternalLink 5001737f1.html.
- Q7107235 wikiPageWikiLink Q127702.
- Q7107235 wikiPageWikiLink Q179991.
- Q7107235 wikiPageWikiLink Q284220.
- Q7107235 wikiPageWikiLink Q321362.
- Q7107235 wikiPageWikiLink Q4027534.
- Q7107235 wikiPageWikiLink Q407646.
- Q7107235 wikiPageWikiLink Q40924.
- Q7107235 wikiPageWikiLink Q415775.
- Q7107235 wikiPageWikiLink Q420566.
- Q7107235 wikiPageWikiLink Q423123.
- Q7107235 wikiPageWikiLink Q476921.
- Q7107235 wikiPageWikiLink Q54237.
- Q7107235 wikiPageWikiLink Q5447188.
- Q7107235 wikiPageWikiLink Q6995207.
- Q7107235 wikiPageWikiLink Q7063594.
- Q7107235 wikiPageWikiLink Q7850941.
- Q7107235 wikiPageWikiLink Q7868.
- Q7107235 wikiPageWikiLink Q79899.
- Q7107235 wikiPageWikiLink Q83330.
- Q7107235 wikiPageWikiLink Q9377.
- Q7107235 comment "Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis.".
- Q7107235 label "Osmotic nephrosis".