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- Q7067708 subject Q9089720.
- Q7067708 abstract "In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities. As of 2007, Mi-2/NuRD was the only known protein complex coupling chromatin remodeling ATPase and chromatin deacetylation enzymatic functions.The NuRD complex contains seven subunits: the histone deacetylase core proteins HDAC1 and HDAC2, the histone-binding proteins RbAp46 and RbAp48, the metastasis-associated proteins MTA1 (or MTA2 / MTA3), the methyl-CpG-binding domain protein MBD3 (or MBD2) and the chromodomain-helicase-DNA-binding protein CHD3 (aka Mi-2alpha) or CHD4 (aka Mi-2beta).The histone deacetylases HDAC1 and HDAC2 and the histone binding proteins RbAp48 and RbAp46 form a core complex shared between NuRD and Sin3-histone deacetylase complexes.Overexpression of Mbd3, a subunit of NuRD, inhibits induction of iPSCs. Depletion of Mbd3, on the other hand, improves reprogramming efficiency, that results in deterministic and synchronized iPS cell reprogramming (near 100% efficiency within seven days from mouse and human cells).".
- Q7067708 wikiPageWikiLink Q14914420.
- Q7067708 wikiPageWikiLink Q174378.
- Q7067708 wikiPageWikiLink Q17861702.
- Q7067708 wikiPageWikiLink Q17861723.
- Q7067708 wikiPageWikiLink Q18026859.
- Q7067708 wikiPageWikiLink Q18031054.
- Q7067708 wikiPageWikiLink Q18031057.
- Q7067708 wikiPageWikiLink Q18033543.
- Q7067708 wikiPageWikiLink Q18033835.
- Q7067708 wikiPageWikiLink Q18033924.
- Q7067708 wikiPageWikiLink Q18040657.
- Q7067708 wikiPageWikiLink Q18043092.
- Q7067708 wikiPageWikiLink Q420927.
- Q7067708 wikiPageWikiLink Q5113739.
- Q7067708 wikiPageWikiLink Q674925.
- Q7067708 wikiPageWikiLink Q7202.
- Q7067708 wikiPageWikiLink Q80863.
- Q7067708 wikiPageWikiLink Q9089720.
- Q7067708 comment "In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities.".
- Q7067708 label "Mi-2/NuRD complex".