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- Q7049004 subject Q7779001.
- Q7049004 subject Q8420225.
- Q7049004 abstract "Non-receptor tyrosine kinases (nRTKs) are cytoplasmic enzymes that are responsible for catalysing the transfer of a phosphate group from a nucleoside triphosphate donor, such as ATP, to tyrosine residues in proteins. Non-receptor tyrosine kinases are a subgroup of protein family tyrosine kinases, enzymes that can transfer the phosphate group from ATP to a tyrosine residue of a protein (phosphorylation). These enzymes regulate many cellular functions by switching on or switching off other enzymes in a cell.Unlike the receptor tyrosine kinases (RTKs), the second subgroup of tyrosine kinases, the non-receptor tyrosine kinases are cytoplasmic enzymes. Thirty-two non-receptor tyrosine kinases have been identified in human cells (EC 2.7.10.2). Non-receptor tyrosine kinases regulate for example cell's growth, proliferation, differentiation, adhesion, migration and apoptosis and they are critical components in the regulation of the immune system.".
- Q7049004 ecNumber "2.7.10.2".
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- Q7049004 ecNumber "2.7".
- Q7049004 name "non-membrane spanning protein tyrosine kinase".
- Q7049004 type Biomolecule.
- Q7049004 type Enzyme.
- Q7049004 type Thing.
- Q7049004 type Q206229.
- Q7049004 type Q8047.
- Q7049004 comment "Non-receptor tyrosine kinases (nRTKs) are cytoplasmic enzymes that are responsible for catalysing the transfer of a phosphate group from a nucleoside triphosphate donor, such as ATP, to tyrosine residues in proteins. Non-receptor tyrosine kinases are a subgroup of protein family tyrosine kinases, enzymes that can transfer the phosphate group from ATP to a tyrosine residue of a protein (phosphorylation).".
- Q7049004 label "Non-receptor tyrosine kinase".
- Q7049004 name "non-membrane spanning protein tyrosine kinase".