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- Q7030497 subject Q7428637.
- Q7030497 subject Q8426518.
- Q7030497 subject Q8645495.
- Q7030497 subject Q8729038.
- Q7030497 subject Q8887197.
- Q7030497 subject Q9056368.
- Q7030497 abstract "Nicomorphine (Vilan, Subellan, Gevilan, MorZet) is the 3,6-dinicotinate ester of morphine. It is a strong opioid agonist analgesic two to three times as potent as morphine with a side effect profile similar to that of dihydromorphine, morphine, and diamorphine. Nicomorphine was patented as Vilan by Lannacher Heilmittel Ges. m.b.H. of Austria in 1957 and was first synthesized in 1904 either there or at another firm in what was then Austria-Hungary. The hydrochloride salt is available as ampoules of 10 mg/ml solution for injection, 5 mg tablets, and 10 mg suppositories. It is possible that other manufacturers distribute 10 mg tablets and other concentrations of injectable nicomorphine in ampoules and multidose vials. It is used, particularly in the German-speaking countries and elsewhere in Central Europe and some other countries in Europe and the former USSR in particular, for post-operative, cancer, chronic non-malignant and other neuropathic pain. It is commonly used in patient-controlled analgesia (PCA) units. The usual starting dose is 5–10 mg given every 3–5 hours.The 3,6-diesters of morphine are drugs with more rapid and complete central nervous system penetration due to increased lipid solubility and other structural considerations. The prototype for this subgroup of semi-synthetic opiates is heroin and the group also includes dipropanoylmorphine, diacetyldihydromorphine, disalicylmorphine and others. Whilst this produces an enhanced "bang" when the drug is administered intravenously, it cannot be distinguished from morphine via other routes, although the different side effect profile, including lower incidence of nausea, is very apparent.".
- Q7030497 atcPrefix "N02".
- Q7030497 atcSuffix "AA04".
- Q7030497 casNumber "639-48-5".
- Q7030497 fdaUniiCode "Y95FRL95FW".
- Q7030497 pubchem "5362460".
- Q7030497 thumbnail Nicomorphine.svg?width=300.
- Q7030497 wikiPageWikiLink Q101487.
- Q7030497 wikiPageWikiLink Q102507.
- Q7030497 wikiPageWikiLink Q1382057.
- Q7030497 wikiPageWikiLink Q1641494.
- Q7030497 wikiPageWikiLink Q186889.
- Q7030497 wikiPageWikiLink Q199602.
- Q7030497 wikiPageWikiLink Q3269441.
- Q7030497 wikiPageWikiLink Q4161086.
- Q7030497 wikiPageWikiLink Q4161314.
- Q7030497 wikiPageWikiLink Q427523.
- Q7030497 wikiPageWikiLink Q4683458.
- Q7030497 wikiPageWikiLink Q5280075.
- Q7030497 wikiPageWikiLink Q60168.
- Q7030497 wikiPageWikiLink Q7428637.
- Q7030497 wikiPageWikiLink Q81225.
- Q7030497 wikiPageWikiLink Q8426518.
- Q7030497 wikiPageWikiLink Q8645495.
- Q7030497 wikiPageWikiLink Q8729038.
- Q7030497 wikiPageWikiLink Q8887197.
- Q7030497 wikiPageWikiLink Q9056368.
- Q7030497 atcPrefix "N02".
- Q7030497 atcSuffix "AA04".
- Q7030497 casNumber "639".
- Q7030497 pubchem "5362460".
- Q7030497 unii "Y95FRL95FW".
- Q7030497 type ChemicalSubstance.
- Q7030497 type Drug.
- Q7030497 type ChemicalObject.
- Q7030497 type Thing.
- Q7030497 type Q8386.
- Q7030497 comment "Nicomorphine (Vilan, Subellan, Gevilan, MorZet) is the 3,6-dinicotinate ester of morphine. It is a strong opioid agonist analgesic two to three times as potent as morphine with a side effect profile similar to that of dihydromorphine, morphine, and diamorphine. Nicomorphine was patented as Vilan by Lannacher Heilmittel Ges. m.b.H. of Austria in 1957 and was first synthesized in 1904 either there or at another firm in what was then Austria-Hungary.".
- Q7030497 label "Nicomorphine".
- Q7030497 depiction Nicomorphine.svg.