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- Q6804652 subject Q8271402.
- Q6804652 abstract "Aspirin causes several different effects in the body, mainly the reduction of inflammation, analgesia (relief of pain), the prevention of clotting, and the reduction of fever. Much of this is believed to be due to decreased production of prostaglandins and TXA2. Aspirin's ability to suppress the production of prostaglandins and thromboxanes is due to its irreversible inactivation of the cyclooxygenase (COX) enzyme. Cyclooxygenase is required for prostaglandin and thromboxane synthesis. Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors. However, other effects of aspirin, such as uncoupling oxidative phosphorylation in mitochondria, and the modulation of signaling through NF-κB, are also being investigated.".
- Q6804652 thumbnail Aspirin-3D-balls.png?width=300.
- Q6804652 wikiPageWikiLink Q101004.
- Q6804652 wikiPageWikiLink Q101026.
- Q6804652 wikiPageWikiLink Q102083.
- Q6804652 wikiPageWikiLink Q1073.
- Q6804652 wikiPageWikiLink Q10863074.
- Q6804652 wikiPageWikiLink Q10876.
- Q6804652 wikiPageWikiLink Q11364.
- Q6804652 wikiPageWikiLink Q12136.
- Q6804652 wikiPageWikiLink Q12140.
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- Q6804652 wikiPageWikiLink Q8271402.
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- Q6804652 type Thing.
- Q6804652 comment "Aspirin causes several different effects in the body, mainly the reduction of inflammation, analgesia (relief of pain), the prevention of clotting, and the reduction of fever. Much of this is believed to be due to decreased production of prostaglandins and TXA2. Aspirin's ability to suppress the production of prostaglandins and thromboxanes is due to its irreversible inactivation of the cyclooxygenase (COX) enzyme. Cyclooxygenase is required for prostaglandin and thromboxane synthesis.".
- Q6804652 label "Mechanism of action of aspirin".
- Q6804652 seeAlso Q410251.
- Q6804652 seeAlso Q5867393.
- Q6804652 seeAlso Q7404457.
- Q6804652 seeAlso Q826103.
- Q6804652 depiction Aspirin-3D-balls.png.