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- Q6731828 subject Q7221143.
- Q6731828 subject Q7440990.
- Q6731828 subject Q8672699.
- Q6731828 abstract "Magnocellular neurosecretory cells are large neuroendocrine cells within the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are also found in smaller numbers in accessory cell groups between these two nuclei, the largest one being the nucleus circularis. There are two types of magnocellular neurosecretory cells, oxytocin-producing cells and vasopressin-producing cells, but a small number can produce both hormones. These cells are neuroendocrine neurons, are electrically excitable, and generate action potentials in response to afferent stimulation.Magnocellular neurosecretory cells in rats (where these neurons have been most extensively studied) in general have a single long varicose axon, which projects to the posterior pituitary. Each axon gives rise to about 10,000 neurosecretory terminals and many axon swellings that store very large numbers of hormone-containing vesicles. These vesicles are released from the axon swellings and nerve terminals by exocytosis in response to calcium entry through voltage-gated ion channels, which occurs when action potentials are propagated down the axons.The cells typically have two or three long dendrites, which also contain large dilations and a very high density of hormone-containing vesicles. Oxytocin and vasopressin can, thus, be released within the brain from these dendrites, as well as into the blood from the terminals in the posterior pituitary gland. However, the release of oxytocin and vasopressin from dendrites is not consistently accompanied by peripheral secretion, as dendritic release is regulated differently. Dendritic release can be triggered by depolarisation, but can also be triggered by the mobilisation of intracellular calcium stores. The dendrites receive most of the synaptic inputs from afferent neurons that regulate the magnocellular neurons; typically a magnocellular neuron receives about 10,000 synapses from afferent neurons.".
- Q6731828 wikiPageWikiLink Q10599959.
- Q6731828 wikiPageWikiLink Q11364.
- Q6731828 wikiPageWikiLink Q1335366.
- Q6731828 wikiPageWikiLink Q14820686.
- Q6731828 wikiPageWikiLink Q1503735.
- Q6731828 wikiPageWikiLink Q164386.
- Q6731828 wikiPageWikiLink Q169960.
- Q6731828 wikiPageWikiLink Q194277.
- Q6731828 wikiPageWikiLink Q323426.
- Q6731828 wikiPageWikiLink Q3338699.
- Q6731828 wikiPageWikiLink Q354550.
- Q6731828 wikiPageWikiLink Q43054.
- Q6731828 wikiPageWikiLink Q444192.
- Q6731828 wikiPageWikiLink Q492272.
- Q6731828 wikiPageWikiLink Q7141374.
- Q6731828 wikiPageWikiLink Q7221143.
- Q6731828 wikiPageWikiLink Q7440990.
- Q6731828 wikiPageWikiLink Q8672699.
- Q6731828 type Thing.
- Q6731828 comment "Magnocellular neurosecretory cells are large neuroendocrine cells within the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are also found in smaller numbers in accessory cell groups between these two nuclei, the largest one being the nucleus circularis. There are two types of magnocellular neurosecretory cells, oxytocin-producing cells and vasopressin-producing cells, but a small number can produce both hormones.".
- Q6731828 label "Magnocellular neurosecretory cell".
- Q6731828 differentFrom Q6731824.