Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q6725509> ?p ?o }
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- Q6725509 subject Q7091330.
- Q6725509 abstract "Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β that are now officially named CCL3 and CCL4, respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They are crucial for immune responses towards infection and inflammation. They activate human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1 (IL-1), IL-6 and TNF-α from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.They are produced by many cells, particularly macrophages, dendritic cells, and lymphocytes. MIP-1 are best known for their chemotactic and proinflammatory effects but can also promote homoeostasis. Biophysical analyses and mathematical modelling has shown that MIP-1 reversibly forms a polydisperse distribution of rod-shaped polymers in solution. Polymerization buries receptor-binding sites of MIP-1, thus depolymerization mutations enhance MIP-1 to arrest monocytes onto activated human endothelium.".
- Q6725509 arm "q".
- Q6725509 band "12".
- Q6725509 band "21".
- Q6725509 chromosome "17".
- Q6725509 entrezgene "6348".
- Q6725509 entrezgene "6351".
- Q6725509 hgncid "10627".
- Q6725509 hgncid "10630".
- Q6725509 locusSupplementaryData "-q23".
- Q6725509 omim "182283".
- Q6725509 omim "182284".
- Q6725509 pdb "1B50".
- Q6725509 pdb "1HUM".
- Q6725509 refseq "NM_002983".
- Q6725509 refseq "NM_002984".
- Q6725509 symbol "CCL3".
- Q6725509 symbol "CCL4".
- Q6725509 symbol "SCYA3, MIP-1α".
- Q6725509 symbol "SCYA4, MIP-1β, LAG1".
- Q6725509 thumbnail 1b53.png?width=300.
- Q6725509 uniprot "P10147".
- Q6725509 uniprot "P13236".
- Q6725509 wikiPageExternalLink searchResults.html?display=both&term=P10147.
- Q6725509 wikiPageExternalLink searchResults.html?display=both&term=P13236.
- Q6725509 wikiPageWikiLink Q107238.
- Q6725509 wikiPageWikiLink Q107988.
- Q6725509 wikiPageWikiLink Q10876.
- Q6725509 wikiPageWikiLink Q1230226.
- Q6725509 wikiPageWikiLink Q14865236.
- Q6725509 wikiPageWikiLink Q14907547.
- Q6725509 wikiPageWikiLink Q14907551.
- Q6725509 wikiPageWikiLink Q1706141.
- Q6725509 wikiPageWikiLink Q18032037.
- Q6725509 wikiPageWikiLink Q184204.
- Q6725509 wikiPageWikiLink Q188417.
- Q6725509 wikiPageWikiLink Q212354.
- Q6725509 wikiPageWikiLink Q220677.
- Q6725509 wikiPageWikiLink Q223143.
- Q6725509 wikiPageWikiLink Q421804.
- Q6725509 wikiPageWikiLink Q421866.
- Q6725509 wikiPageWikiLink Q463418.
- Q6725509 wikiPageWikiLink Q658145.
- Q6725509 wikiPageWikiLink Q7091330.
- Q6725509 wikiPageWikiLink Q766195.
- Q6725509 altsymbols "SCYA3, MIP-1α".
- Q6725509 altsymbols "SCYA4, MIP-1β, LAG1".
- Q6725509 arm "q".
- Q6725509 band "12".
- Q6725509 band "21".
- Q6725509 chromosome "17".
- Q6725509 entrezgene "6348".
- Q6725509 entrezgene "6351".
- Q6725509 hgncid "10627".
- Q6725509 hgncid "10630".
- Q6725509 locussupplementarydata "-q23".
- Q6725509 name Q14907547.
- Q6725509 name Q14907551.
- Q6725509 omim "182283".
- Q6725509 omim "182284".
- Q6725509 pdb "1".
- Q6725509 refseq "NM_002983".
- Q6725509 refseq "NM_002984".
- Q6725509 symbol Q14907547.
- Q6725509 symbol "CCL4".
- Q6725509 uniprot "P10147".
- Q6725509 uniprot "P13236".
- Q6725509 type Biomolecule.
- Q6725509 type Protein.
- Q6725509 type Thing.
- Q6725509 type Q206229.
- Q6725509 type Q8054.
- Q6725509 comment "Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β that are now officially named CCL3 and CCL4, respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They are crucial for immune responses towards infection and inflammation.".
- Q6725509 label "Macrophage inflammatory protein".
- Q6725509 depiction 1b53.png.
- Q6725509 name "chemokine (C-C motif) ligand 3".
- Q6725509 name "chemokine (C-C motif) ligand 4".